CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6215
Family Name Neprilysin inhibitor AGN-PC-047EOK family
No. of Seeds 7 No. of Other Members 4
Family Centroid CFAMM00370903 Functional Category Bioactive
Superfamily Neprilysin and Cathepsin K Binder Superfamily
Class Class 4400

Cousin Family NamesSeedsMembers
Alpha-1B adrenergic receptor Ligand Lisdexamfetamine Family 14 443
ATP-sensitive inward rectifier potassium channel 10 Ligand Ace... 2 64
Neprilysin Inhibitor Thiorphan Family 41 68
Carbonic anhydrase 2 Inhibitor N-benzyl-4-sulfamoyl-benzamide ... 12 44
Neuromedin-K receptor Ligand PD-157672 Family 9 37
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(6... 1 12
Cathepsin B and Cathepsin S Inhibitor Ac-hphe-leu-ala-leuvsme ... 17 51
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-p... 6 19
Genome polyprotein Inhibitor Acdif-ile-cha-cys Family 37 96
Aminopeptidase N Inhibitor 2-cinnamamido-n4-hexyl-n1-hydroxysu... 24 8
Neprilysin inhibitor AGN-PC-047EP1 family 1 0
Matrix metalloproteinase-9 and Stromelysin-1 inhibitor N-[(2S)... 1 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 0
Histone deacetylase 6 and Histone deacetylase 1 inhibitor AGN-... 3 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00370907 CHEMBL157663 Bioactive AGN-PC-047EOH
CFAMM00370906 CHEMBL155417 Bioactive AGN-PC-047EOQ
CFAMM00370904 CHEMBL157823 Bioactive AGN-PC-000H5E
CFAMM00370903 CHEMBL156012 Bioactive AGN-PC-047EOK
CFAMM00370910 CHEMBL156374 Bioactive sodium;2-[[(2R)-2-benzyl-3-sulfanylpropanoyl]amino]ethanesulfonate
CFAMM00370902 CHEMBL157625 Bioactive sodium;2-[[(2S)-2-benzyl-3-sulfanylpropanoyl]amino]ethanesulfonate
CFAMM00370909 CHEMBL440183 Bioactive AGN-PC-047EOV

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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