CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6227
Family Name Cellular tumor antigen p53 inhibitor CHEMBL1554992 family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00370996 Functional Category Bioactive
Superfamily Nuclear receptor ROR-gamma and Prostaglandin E2 receptor EP3 subtype Binder Superfamily
Class Class 3220

Cousin Family NamesSeedsMembers
D(2) dopamine receptor and D(3) dopamine receptor ligand indol... 4 123
Motilin receptor Ligand GSK962040 Family 30 457
Pan-DAC Inhibitor AR-42 Family 21 153
Intedanib family 7 54
Dual specificity mitogen-activated protein kinase kinase Inhib... 7 69
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Caspase-3 Inhibitor 5-(pyrrolidin-1-ylsulfonyl)indoline-2,3-di... 5 35
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor N-(4-s... 12 92
Potassium voltage-gated channel subfamily A member 5 Ligand N-... 8 32
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
Integrin beta-3 Inhibitor L-750034 Family 7 38
Aromatase Inhibitor 3-(4-amino-phenyl)-1-methyl-pyrrolidine-2,... 4 8
Acetyl-CoA acetyltransferase, mitochondrial Inhibitor Octanoic... 4 14
Aurora kinase B Inhibitor Hesperadin Family 1 1
Beta-secretase 1 and Cathepsin D Inhibitor GRL-7234 Family 17 148
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 12
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 15 129
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
Apolipoprotein B-100 and Microsomal triglyceride transfer prot... 6 5
Chymotrypsin-like elastase family member 1 and Neutrophil elas... 1 12
D(2) dopamine receptor and D(3) dopamine receptor ligand 1,1-d... 2 7
Cannabinoid receptor 2 ligand 4-methyl-3-piperidin-1-ylsulfony... 2 0
Transient receptor potential cation channel subfamily V member... 9 38
Histamine receptor H3 ligand N-[2-methyl-4-[(3S)-3-[(2S)-2-met... 10 7
5-hydroxytryptamine receptor 7 ligand 3-ethyl-3-[4-[4-(4-fluor... 3 1
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 7 12
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibi... 1 0
Neuropeptide Y receptor type 5 ligand AGN-PC-01NS0Z family 1 0
Kappa-type opioid receptor and Delta-type opioid receptor liga... 3 1
Protein farnesyltransferase subunit beta and Protein farnesylt... 4 13
Serine/threonine-protein kinase Chk1 inhibitor 6-oxo-9-(2-oxo-... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00370993 CHEMBL1794058 Bioactive GW278681X

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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