CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Disintegrin and metalloproteinase domain-containing protein 17 inhibitor SureCN13200797 family
No. of Seeds 28 No. of Other Members 10
Family Centroid CFAMM00313806 Functional Category Bioactive with Natural Product
Superfamily Disintegrin and metalloproteinase domain-containing protein 17 Binder Superfamily
Class Class 2604

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme Inhibitor Moexipril Family 5 469
Endothelin-1 receptor Ligand Atrasentan Family 127 336
A disintegrin and metalloproteinase with thrombospondin motifs... 7 119
Delta-type opioid receptor Ligand Bw 373u86 Family 31 146
C-C chemokine receptor type 5 Ligand E-913 Family 6 44
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 3 89
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 16
Plasmepsin-2 Inhibitor PS-662477 Family 7 55
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Histamine H3 receptor Ligand A-349821 Family 49 228
Interstitial collagenase Inhibitor N-hydroxycarbamoylmethyl-4-... 5 24
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 5 26
Neutrophil elastase Inhibitor N,n-bis(cyanomethyl)-3,4-dimetho... 3 30
Fatty-acid amide hydrolase 1 Inhibitor 3'-carbamoylbiphenyl-3-... 8 50
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
D(2) dopamine receptor Ligand Epidepride Family 31 66
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 5 17
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 2 0
Disintegrin and metalloproteinase domain-containing protein 17... 2 0
Disintegrin and metalloproteinase domain-containing protein 17... 1 2
Neutrophil elastase inhibitor (2S)-N-[(3S)-6-benzamido-5,5-dif... 6 10
D(4) dopamine receptor and D(3) dopamine receptor ligand N-[(3... 2 11
Disintegrin and metalloproteinase domain-containing protein 17... 3 0
Disintegrin and metalloproteinase domain-containing protein 17... 1 0
Disintegrin and metalloproteinase domain-containing protein 17... 3 0
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL14038... 1 9
Matrix metalloproteinase-9 and Interstitial collagenase inhibi... 2 13
Pol polyprotein inhibitor CHEMBL305466 family 4 7
Angiotensin-converting enzyme and Angiotensin-converting enzym... 3 13
Growth hormone secretagogue receptor type 1 ligand 2-(2-acetyl... 2 0
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 12 54
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 1
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 1 0
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 2 3
Melanin-concentrating hormone receptor 1 ligand (3S)-3-[[5-(4-... 4 5
Beta-secretase 1 inhibitor (2S)-2-[(3S)-3-acetamido-3-butan-2-... 6 3
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 15 4
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 3
Caspase-1 and Caspase-8 inhibitor N-[(6S)-1-[2-[[(3S)-2-hydrox... 3 1
Kappa-type opioid receptor and Delta-type opioid receptor liga... 1 3
Caspase-1 inhibitor (3S)-3-[2-[3-(naphthalene-1-carbonylamino)... 13 5
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 3 1
Sigma non-opioid intracellular receptor 1 and D(3) dopamine re... 26 8
Melanin-concentrating hormone receptor 1 ligand N-methyl-N-[(3... 2 2
Muscarinic acetylcholine receptor M3 ligand N-[[3-[3-[(3-methy... 5 2
C-C chemokine receptor type 3 and Probable C-C chemokine recep... 5 2
Dipeptidyl peptidase 4 inhibitor SureCN664019 family 4 5
Caspase-3 inhibitor N-[(2-methoxyphenyl)methyl]-3-oxo-1,2-benz... 3 0


External ID

Functional Category

Molecule Name

CFAMM00313798 CHEMBL1288090 Bioactive SureCN8232799
CFAMM00313807 CHEMBL1288152 Bioactive SureCN13201083
CFAMM00313810 CHEMBL1288059 Bioactive SureCN13200449
CFAMM00313788 CHEMBL1288121 Bioactive SureCN8227024
CFAMM00313817 CHEMBL1288182 Bioactive SureCN13201087
CFAMM00313799 CHEMBL1288091 Bioactive SureCN13200914
CFAMM00313806 CHEMBL1287998 Bioactive SureCN13200797
CFAMM00313821 CHEMBL1090749 Bioactive SureCN7899745
CFAMM00313809 CHEMBL1084661 Bioactive AGN-PC-07ZAIP
CFAMM00313828 CHEMBL1222804 Bioactive 4-[4-[(4R)-4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]phenyl]benzamide
CFAMM00313787 CHEMBL1288122 Bioactive SureCN13200231
CFAMM00313816 CHEMBL1089042 Bioactive SureCN8227108
CFAMM00313794 CHEMBL1090736 Bioactive SureCN5956316
CFAMM00313827 CHEMBL1088216 Bioactive AGN-PC-04TBOJ
CFAMM00313814 CHEMBL1089728 Bioactive AGN-PC-00BFGK
CFAMM00313819 CHEMBL1288240 Bioactive SureCN8228822
CFAMM00313826 CHEMBL1288028 Bioactive SureCN12862655
CFAMM00313802 CHEMBL1222720 Bioactive (5R)-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(pyrrolidine-1-carbonyl)phenyl]imidazolidine-2,4-dione
CFAMM00313825 CHEMBL1288029 Bioactive SureCN13200221
CFAMM00313812 CHEMBL1288151 Bioactive SureCN13201081
CFAMM00313790 CHEMBL1288060 Bioactive SureCN13200912
CFAMM00313801 CHEMBL1288212 Bioactive SureCN13201147
CFAMM00313830 CHEMBL1222803 Bioactive methyl 4-[4-[(4R)-4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]phenyl]benzoate
CFAMM00313808 CHEMBL1222588 Bioactive SureCN8227332
CFAMM00313824 CHEMBL1287881 Bioactive SureCN10111745
CFAMM00313811 CHEMBL1223076 Bioactive 5-[4-[(4R)-4-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-2,5-dioxoimidazolidin-4-yl]phenyl]-5-methylimidazolidine-2,4-dione
CFAMM00313818 CHEMBL1288183 Bioactive SureCN8236999
CFAMM00313800 CHEMBL1288211 Bioactive SureCN10131674

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



118187 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543