CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6258
Family Name Integrin beta-1 and Integrin alpha-4 inhibitor SureCN6367561 family
No. of Seeds 20 No. of Other Members 12
Family Centroid CFAMM00369904 Functional Category Bioactive
Superfamily Integrin beta-1 and Integrin alpha-4 Binder Superfamily 3
Class Class 2455

Cousin Family NamesSeedsMembers
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN6368456 f... 3 23
Integrin beta-1 and Integrin alpha-4 inhibitor (3R)-3-[[(2S)-1... 12 0
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN6368512 f... 23 21
Integrin beta-1 and Integrin alpha-4 inhibitor (3R)-3-[[(2S)-1... 2 1
Integrin beta-1 and Integrin alpha-4 inhibitor (3R)-3-[[(2S)-1... 3 0
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN5686971 f... 19 1
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 2 0
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN5686807 f... 7 2
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[4-(ben... 12 20
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[1-(ben... 6 5
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(4S)-3... 3 24
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN6453971 f... 3 4
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 9 2
Integrin beta-1 and Integrin alpha-4 inhibitor (4S)-4-[benzene... 7 0
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN5686827 f... 7 3
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN6367731 f... 1 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 2 0
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN5687185 f... 7 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[2-[car... 1 0
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN6373390 f... 2 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-1-(3,5-dic... 1 0
Integrin beta-1 and Integrin alpha-4 inhibitor (3R)-3-[[(2S)-1... 1 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00371165 CHEMBL155800 Bioactive (2S)-2-[[(2S)-1-(3,5-dichlorophenyl)sulfonyl-2-methylpyrrolidine-2-carbonyl]amino]-3-[4-(trifluoromethoxy)phenyl]propanoic acid
CFAMM00371164 CHEMBL43213 Bioactive (2S)-2-[[(2S)-1-(3,5-dichlorophenyl)sulfonyl-2-methylpyrrolidine-2-carbonyl]amino]-3-[4-(morpholine-4-carbonyloxy)phenyl]propanoic acid
CFAMM00371162 CHEMBL42703 Bioactive (2S)-2-[[(2S)-1-(3,5-dichlorophenyl)sulfonyl-2-methylpyrrolidine-2-carbonyl]amino]-3-[3-(pyrrolidine-1-carbonyloxy)phenyl]propanoic acid
CFAMM00371175 CHEMBL345450 Bioactive (2S)-2-[[(2S)-1-(3,5-dichlorophenyl)sulfonyl-2-methylpyrrolidine-2-carbonyl]amino]-3-(4-methoxyphenyl)propanoic acid
CFAMM00371168 CHEMBL44204 Bioactive SureCN6372369
CFAMM00371161 CHEMBL347352 Bioactive (2S)-2-[[(2S)-1-(3,5-dichlorophenyl)sulfonylpyrrolidine-2-carbonyl]amino]-3-[4-(trifluoromethoxy)phenyl]propanoic acid
CFAMM00371167 CHEMBL44357 Bioactive (2S)-2-[[(2S)-1-(3,5-dichlorophenyl)sulfonyl-2-methylpyrrolidine-2-carbonyl]amino]-3-[4-(pyrrolidine-1-carbonyloxy)phenyl]propanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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