CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6266
Family Name Integrin beta-1 and Integrin alpha-4 inhibitor SureCN6368512 family
No. of Seeds 23 No. of Other Members 21
Family Centroid CFAMM00371279 Functional Category Bioactive
Superfamily Integrin beta-1 and Integrin alpha-4 Binder Superfamily 4
Class Class 3137

Cousin Family NamesSeedsMembers
Thymidylate synthase Inhibitor Sp-876 Family 7 117
Pol polyprotein inhibitor Lysine Sulfonamide 11c family 3 73
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN6368456 f... 3 23
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN6367561 f... 20 12
Integrin beta-1 and Integrin alpha-4 inhibitor (3R)-3-[[(2S)-1... 2 1
Integrin beta-1 and Integrin alpha-4 inhibitor (3R)-3-[[(2S)-1... 3 0
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN5686971 f... 19 1
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 2 0
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN5686807 f... 7 2
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-[(2,6... 7 3
Angiotensin-converting enzyme inhibitor (2S)-2-[[(2S)-1-[carbo... 2 5
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-N-... 7 1
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN5687185 f... 7 0
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN6373390 f... 2 0
72 kDa type IV collagenase and Stromelysin-1 inhibitor (3R)-3-... 3 2
Integrin beta-1 and Integrin alpha-4 inhibitor (3R)-3-[[(2S)-1... 1 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S,3S)-3-[[(2S... 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00371260 CHEMBL348411 Bioactive SureCN6368438
CFAMM00371273 CHEMBL160568 Bioactive (2S)-2-[[(2S)-1-(3,5-dichlorophenyl)sulfonyl-2-methylpyrrolidine-2-carbonyl]amino]-3-(4-ethylphenyl)propanoic acid
CFAMM00371299 CHEMBL423600 Bioactive (2S)-2-[[(2S)-1-(3,5-dichlorophenyl)sulfonylpyrrolidine-2-carbonyl]amino]-3-(2-fluorophenyl)propanoic acid
CFAMM00371286 CHEMBL160252 Bioactive SureCN6368398
CFAMM00371266 CHEMBL347037 Bioactive (2S)-3-(3-chlorophenyl)-2-[[(2S)-1-(3,5-dichlorophenyl)sulfonyl-2-methylpyrrolidine-2-carbonyl]amino]propanoic acid
CFAMM00371279 CHEMBL347903 Bioactive SureCN6368512
CFAMM00371285 CHEMBL345193 Bioactive (2S)-2-[[(2S)-1-(3,5-dichlorophenyl)sulfonylpyrrolidine-2-carbonyl]amino]-3-(3,4-difluorophenyl)propanoic acid
CFAMM00371271 CHEMBL423603 Bioactive SureCN6367880
CFAMM00371284 CHEMBL347643 Bioactive (2S)-3-(3-chlorophenyl)-2-[[(2S)-1-(3,5-dichlorophenyl)sulfonylpyrrolidine-2-carbonyl]amino]propanoic acid
CFAMM00371297 CHEMBL160171 Bioactive (2S)-2-[[(2S)-1-(3,5-dichlorophenyl)sulfonylpyrrolidine-2-carbonyl]amino]-3-[3-(trifluoromethyl)phenyl]propanoic acid
CFAMM00371264 CHEMBL349096 Bioactive (2S)-2-[[(2S)-1-(3,5-dichlorophenyl)sulfonyl-2-methylpyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
CFAMM00371283 CHEMBL348353 Bioactive (2S)-2-[[(2S)-1-(3,5-dichlorophenyl)sulfonylpyrrolidine-2-carbonyl]amino]-3-(4-ethylphenyl)propanoic acid
CFAMM00371263 CHEMBL158726 Bioactive (2S)-2-[[(2S)-1-(3,5-dichlorophenyl)sulfonyl-2-methylpyrrolidine-2-carbonyl]amino]-3-(4-fluorophenyl)propanoic acid
CFAMM00371276 CHEMBL350913 Bioactive (2S)-2-[[(2S)-1-(3,5-dichlorophenyl)sulfonyl-2-methylpyrrolidine-2-carbonyl]amino]-3-(4-iodophenyl)propanoic acid
CFAMM00371289 CHEMBL160920 Bioactive (2S)-2-[[(2S)-1-(3,5-dichlorophenyl)sulfonyl-2-methylpyrrolidine-2-carbonyl]amino]-3-(2-fluorophenyl)propanoic acid
CFAMM00371303 CHEMBL345613 Bioactive (2S)-2-[[(2S)-1-(3,5-dichlorophenyl)sulfonyl-2-methylpyrrolidine-2-carbonyl]amino]-3-[4-(trifluoromethyl)phenyl]propanoic acid
CFAMM00371282 CHEMBL158891 Bioactive SureCN6372412
CFAMM00371269 CHEMBL347935 Bioactive (2S)-2-[[(2S)-1-(3,5-dichlorophenyl)sulfonylpyrrolidine-2-carbonyl]amino]-3-(3,5-difluorophenyl)propanoic acid
CFAMM00371262 CHEMBL348651 Bioactive (2S)-2-[[(2S)-1-(3,5-dichlorophenyl)sulfonyl-2-methylpyrrolidine-2-carbonyl]amino]-3-(3-fluorophenyl)propanoic acid
CFAMM00371301 CHEMBL155872 Bioactive (2S)-2-[[(2S)-1-(3,5-dichlorophenyl)sulfonylpyrrolidine-2-carbonyl]amino]-3-(3-fluorophenyl)propanoic acid
CFAMM00371268 CHEMBL156253 Bioactive (2S)-3-(4-chlorophenyl)-2-[[(2S)-1-(3,5-dichlorophenyl)sulfonyl-2-methylpyrrolidine-2-carbonyl]amino]propanoic acid
CFAMM00371294 CHEMBL160745 Bioactive (2S)-3-(2-chlorophenyl)-2-[[(2S)-1-(3,5-dichlorophenyl)sulfonyl-2-methylpyrrolidine-2-carbonyl]amino]propanoic acid
CFAMM00371287 CHEMBL348037 Bioactive SureCN6368117

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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