CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6267
Family Name 72 kDa type IV collagenase and Matrix metalloproteinase-9 inhibitor (2R)-2-[[4-[(4-bromobenzoyl)amino]phenyl]sulfonylamino]-3-(1H-indol-3-yl)propanoic acid family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00371305 Functional Category Bioactive
Superfamily Fatty acid-binding protein, adipocyte Inhibitor 2-(3-methyl-indole-1-sulfonyl)-benzoic Acid Superfamily
Class Class 2185

Cousin Family NamesSeedsMembers
Indoleamine 2,3-dioxygenase 1 Inhibitor L-tryptophan Family 8 328
Thromboxane-A synthase Inhibitor CGS-22652 Family 37 95
Endothelin B receptor Ligand IRL-2500 Family 34 87
Thromboxane A2 receptor and Thromboxane-A synthase ligand AGN-... 4 19
Cathepsin L1 inhibitor Bio2_000267 family 9 1
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 4
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 5 1
Pol polyprotein inhibitor AC1LAHQ9 family 8 15
Pancreatic alpha-amylase and Gastrin/cholecystokinin type B re... 7 1
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 4 3
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 4 1
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 1 1
Neprilysin and Endothelin-converting enzyme 1 inhibitor (2S)-2... 5 0
Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor [2-(me... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00371305 CHEMBL155874 Bioactive (2R)-2-[[4-[(4-bromobenzoyl)amino]phenyl]sulfonylamino]-3-(1H-indol-3-yl)propanoic acid
CFAMM00371304 CHEMBL199917 Bioactive (2S)-2-[[4-[(4-bromobenzoyl)amino]phenyl]sulfonylmethyl]-3-(1H-indol-3-yl)propanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48711 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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