CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6277
Family Name Neuropeptide S receptor and Survival motor neuron protein ligand CHEMBL1559419 family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00371353 Functional Category Bioactive with Natural Product
Superfamily Retinal dehydrogenase 1 and Survival motor neuron protein Binder Superfamily
Class Class 3126

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme Inhibitor Moexipril Family 5 469
Endothelin-1 receptor Ligand Atrasentan Family 127 336
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 131
Urotensin-2 receptor Ligand JNJ-28318706 Family 4 227
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Liver carboxylesterase 1 Inhibitor SCH-48375 Family 2 28
Integrin beta-1 and Integrin alpha-4 inhibitor (3S)-3-(3,4-dim... 5 61
D(4) dopamine receptor and D(2) dopamine receptor ligand 2-[4-... 2 6
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 1
Substance-P receptor ligand N-[1-[acetyl-[(2-methoxyphenyl)met... 3 9
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 10
Transient receptor potential cation channel subfamily V member... 1 5
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 4 4
Endothelin B receptor and Endothelin-1 receptor ligand SureCN8... 6 4
D(3) dopamine receptor and D(2) dopamine receptor ligand (E)-3... 2 3
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 4
Survival motor neuron protein and DNA-(apurinic or apyrimidini... 1 5
Histamine H3 receptor ligand 5-[4-[3-[(2R)-2-methylpyrrolidin-... 2 3
Melanin-concentrating hormone receptor 1 and Potassium voltage... 3 6
Integrin beta-3 and Integrin alpha-V inhibitor (3R)-3-(1,3-ben... 5 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 2 13
Sigma non-opioid intracellular receptor 1 ligand (5S)-5-[[4-(1... 4 18
Sigma non-opioid intracellular receptor 1 ligand (5S)-5-[(4-hy... 1 5
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075HBO ... 2 44


External ID

Functional Category

Molecule Name

CFAMM00371351 CHEMBL322222 Bioactive AC1LZASY

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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