CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6282
Family Name Peptide deformylase inhibitor (2R)-2-[[formyl(hydroxy)amino]methyl]-N-[(2S)-1-[4-(methanesulfonamido)phenyl]-3,3-dimethyl-1-oxobutan-2-yl]hexanamide family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00371374 Functional Category Bioactive
Superfamily Peptide deformylase Binder Superfamily
Class Class 3289

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Procainamid... 7 291
DNA Binder Procarbazine Family 8 358
Histone deacetylase 1 Inhibitor Vorinostat Family 26 138
Pan-DAC Inhibitor AR-42 Family 21 153
Neutrophil elastase Inhibitor FK-706 Family 8 85
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 40 87
Histone deacetylase 1 Inhibitor 8-(3-benzoyl-ureido)-octanoic ... 7 13
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 13
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 7
Cathepsin S Inhibitor N-(1-oxobutan-2-yl)-3-(trifluoromethyl)b... 2 10
Aminopeptidase N Inhibitor N1,2-dibenzyl-n3-hydroxymalonamide ... 5 23
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 15 129
5-hydroxytryptamine receptor 2A Ligand N-(1-(4-nitrobenzyl)pip... 4 6
Aminopeptidase N Inhibitor 2-cinnamamido-n4-hexyl-n1-hydroxysu... 24 8
72 kDa type IV collagenase and Matrilysin inhibitor (2S,3R)-N-... 1 0
Peptide deformylase inhibitor (2R)-N-[(2S)-1-(4-fluorophenyl)-... 4 0
Peptide deformylase inhibitor (2R)-2-(cyclopentylmethyl)-3-[fo... 11 2
Peptide deformylase inhibitor (2R)-2-(cyclopentylmethyl)-N-[(2... 3 0
Peptide deformylase inhibitor (2S)-N-benzoyl-1-[(2R)-2-(cyclop... 2 2
Transient receptor potential cation channel subfamily A member... 1 1
Neutrophil elastase inhibitor 1-[(2S)-3-methyl-2-[(4-nitrobenz... 1 1
Glucose-dependent insulinotropic receptor ligand AGN-PC-04UO8L... 2 2


External ID

Functional Category

Molecule Name

CFAMM00371374 CHEMBL155998 Bioactive (2R)-2-[[formyl(hydroxy)amino]methyl]-N-[(2S)-1-[4-(methanesulfonamido)phenyl]-3,3-dimethyl-1-oxobutan-2-yl]hexanamide
CFAMM00371372 CHEMBL346544 Bioactive (2R)-N-[(2S)-1-(4-aminophenyl)-3,3-dimethyl-1-oxobutan-2-yl]-2-[[formyl(hydroxy)amino]methyl]hexanamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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