CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6307
Family Name Peptide deformylase inhibitor (2R)-2-(cyclopentylmethyl)-3-[formyl(hydroxy)amino]-N-[(2S)-1-[4-[4-(2-hydroxyethyl)piperazin-1-yl]phenyl]-3,3-dimethyl-1-oxobutan-2-yl]propanamide family
No. of Seeds 11 No. of Other Members 2
Family Centroid CFAMM00371553 Functional Category Bioactive
Superfamily Peptide deformylase and Neutrophil elastase Binder Superfamily
Class Class 2844

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Procainamid... 7 291
Pan-DAC Inhibitor AR-42 Family 21 153
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 15 129
Lethal factor inhibitor (2R)-2-(4-fluoro-3,5-dimethylanilino)-... 11 8
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-N-... 2 7
Peptide deformylase inhibitor (2R)-2-[[formyl(hydroxy)amino]me... 2 1
Peptide deformylase inhibitor (2R)-2-(cyclopentylmethyl)-N-[(2... 3 0
Tyrosine-protein kinase ITK/TSK and Mast/stem cell growth fact... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00371550 CHEMBL157738 Bioactive (2R)-2-(cyclopentylmethyl)-3-[formyl(hydroxy)amino]-N-[(2S)-1-[4-(4-hydroxypiperidin-1-yl)phenyl]-3,3-dimethyl-1-oxobutan-2-yl]propanamide
CFAMM00371543 CHEMBL346291 Bioactive (2R)-2-(cyclopentylmethyl)-N-[(2S)-3,3-dimethyl-1-[4-[4-(2-morpholin-4-ylethyl)piperazin-1-yl]phenyl]-1-oxobutan-2-yl]-3-[formyl(hydroxy)amino]propanamide
CFAMM00371549 CHEMBL160164 Bioactive (2R)-2-(cyclopentylmethyl)-N-[(2S)-1-[3-fluoro-4-(4-hydroxypiperidin-1-yl)phenyl]-3,3-dimethyl-1-oxobutan-2-yl]-3-[formyl(hydroxy)amino]propanamide
CFAMM00371542 CHEMBL350211 Bioactive (2R)-2-(cyclopentylmethyl)-N-[(2S)-1-[3-fluoro-4-[4-(2-morpholin-4-ylethyl)piperazin-1-yl]phenyl]-3,3-dimethyl-1-oxobutan-2-yl]-3-[formyl(hydroxy)amino]propanamide
CFAMM00371548 CHEMBL156414 Bioactive (2R)-2-(cyclopentylmethyl)-N-[(2S)-1-(3-fluoro-4-morpholin-4-ylphenyl)-3,3-dimethyl-1-oxobutan-2-yl]-3-[formyl(hydroxy)amino]propanamide
CFAMM00371541 CHEMBL409416 Bioactive (2R)-2-(cyclopentylmethyl)-N-[(2S)-3,3-dimethyl-1-oxo-1-[4-[4-(2-pyrrolidin-1-ylethyl)piperazin-1-yl]phenyl]butan-2-yl]-3-[formyl(hydroxy)amino]propanamide
CFAMM00371554 CHEMBL157687 Bioactive (2R)-2-(cyclopentylmethyl)-N-[(2S)-1-[3-fluoro-4-[4-(2-pyrrolidin-1-ylethyl)piperazin-1-yl]phenyl]-3,3-dimethyl-1-oxobutan-2-yl]-3-[formyl(hydroxy)amino]propanamide
CFAMM00371553 CHEMBL156187 Bioactive (2R)-2-(cyclopentylmethyl)-3-[formyl(hydroxy)amino]-N-[(2S)-1-[4-[4-(2-hydroxyethyl)piperazin-1-yl]phenyl]-3,3-dimethyl-1-oxobutan-2-yl]propanamide
CFAMM00371545 CHEMBL348888 Bioactive (2R)-2-(cyclopentylmethyl)-N-[(2S)-3,3-dimethyl-1-(4-morpholin-4-ylphenyl)-1-oxobutan-2-yl]-3-[formyl(hydroxy)amino]propanamide
CFAMM00371551 CHEMBL156163 Bioactive (2R)-2-(cyclopentylmethyl)-N-[(2S)-1-[3-fluoro-4-[4-(2-hydroxyethyl)piperazin-1-yl]phenyl]-3,3-dimethyl-1-oxobutan-2-yl]-3-[formyl(hydroxy)amino]propanamide
CFAMM00371544 CHEMBL160493 Bioactive (2R)-N-[(2S)-3,3-dimethyl-1-(4-morpholin-4-ylphenyl)-1-oxobutan-2-yl]-2-[[formyl(hydroxy)amino]methyl]hexanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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