CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Muscarinic acetylcholine receptor M1 and Muscarinic acetylcholine receptor M3 ligand 1-[2-(3-chlorophenyl)phenyl]-3-piperidin-4-ylpropan-1-ol family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00313916 Functional Category Bioactive
Superfamily potassium channel subunit alpha-1 ligand phenanthrene derivative Halofantrine Lumefantrine Superfamily
Class Class 225

Cousin Family NamesSeedsMembers
Muscarinic acetylcholine receptor M1 Ligand Trihexyphenidyl Fa... 14 199
Histamine H1 receptor Ligand Chlophedianol Family 4 46
Sodium/potassium-transporting ATPase subunit alpha-1 inhibitor... 1 1
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Sulfen... 5 13
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 5 14
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 9 7
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor Liga... 1 8
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 4
Nociceptin receptor ligand SB-612111 family 1 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 1 0
Dibenzocycloheptenes Metabolite E-10-Hydroxynortriptyline Family 1 0


External ID

Functional Category

Molecule Name

CFAMM00313916 CHEMBL1084850 Bioactive 1-[2-(3-chlorophenyl)phenyl]-3-piperidin-4-ylpropan-1-ol

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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