CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6333
Family Name Protein kinase C alpha type and Protein kinase C delta type inhibitor AC1L9UQM family
No. of Seeds 4 No. of Other Members 37
Family Centroid CFAMM00371772 Functional Category Bioactive
Superfamily Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J33) Inhibitor Bms 791325 Superfamily
Class Class 97

Cousin Family NamesSeedsMembers
High affinity nerve growth factor receptor Ligand Lestaurtinib... 6 126
B-lymphocyte antigen CD20 Inhibitor Rituxan Immunology Family 10 17
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 12 197
NF-kappa-B and Protein kinase C zeta type Inhibitor Go6976 Family 9 71
DNA topoisomerase 1 Inhibitor KT6006 Family 3 53
Vascular endothelial growth factor receptor 2 Ligand Isoindoli... 11 36
Serine/threonine-protein kinase Chk1 Inhibitor A-432411 Family 4 70
Platelet-derived growth factor receptor alpha and Platelet-der... 4 54
Serine/threonine-protein kinase Chk1 and Wee1-like protein kin... 2 101
High affinity nerve growth factor receptor and Mitogen-activat... 2 7
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-366... 5 75
Vascular endothelial growth factor receptor 2 and Angiopoietin... 4 1
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 4 41
Renin inhibitor SureCN1144364 family 3 15
Poly [ADP-ribose] polymerase 1 inhibitor SureCN5002485 family 2 11
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 16
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 15
NS5B protein inhibitor AGN-PC-00A17Z family 1 23
RAC-alpha serine/threonine-protein kinase inhibitor 5-[5-[(2S)... 14 2
Angiopoietin-1 receptor and Vascular endothelial growth factor... 7 2
RAC-beta serine/threonine-protein kinase and 3-phosphoinositid... 1 1
Tyrosine-protein kinase JAK3 inhibitor CHEMBL234066 family 1 2
Wee1-like protein kinase and Serine/threonine-protein kinase C... 3 51
Serine/threonine-protein kinase Chk1 and Wee1-like protein kin... 3 12
Wee1-like protein kinase and Serine/threonine-protein kinase C... 8 0
Protein kinase C alpha type and Protein kinase C delta type in... 2 0
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 6 8
Vascular endothelial growth factor receptor 2 ligand SureCN235... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00371755 CHEMBL348902 Bioactive Indolocarbazole deriv. 3n
CFAMM00371753 CHEMBL156433 Bioactive SureCN8127265
CFAMM00371772 CHEMBL345593 Bioactive AC1L9UQM

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

23964 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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