CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6350
Family Name Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha and Protein farnesyltransferase subunit beta inhibitor AGN-PC-00EHLE family
No. of Seeds 8 No. of Other Members 0
Family Centroid CFAMM00371877 Functional Category Bioactive
Superfamily Protein farnesyltransferase subunit beta Inhibitor A-313326 Superfamily
Class Class 2754

Cousin Family NamesSeedsMembers
Protein farnesyltransferase subunit beta Inhibitor A-313326 Fa... 85 149
Potassium voltage-gated channel subfamily H member 2 Ligand (1... 64 70
Cathepsin S and Cathepsin K inhibitor SureCN1629664 family 10 11
Extracellular calcium-sensing receptor ligand SureCN2972008 fa... 4 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 6 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 19 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 8 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 21 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN6... 8 12
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 1
Cytochrome P450 26A1 and Cytochrome P450 3A4 inhibitor 3-[6-[(... 14 26
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 7 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 7 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 6 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00371878 CHEMBL25620 Bioactive AGN-PC-074A0U
CFAMM00371877 CHEMBL364792 Bioactive AGN-PC-00EHLE
CFAMM00371883 CHEMBL158139 Bioactive SureCN5089090
CFAMM00371876 CHEMBL363041 Bioactive AGN-PC-075G1Q
CFAMM00371882 CHEMBL363524 Bioactive AGN-PC-075G5K
CFAMM00371881 CHEMBL156523 Bioactive AGN-PC-007UBV
CFAMM00371880 CHEMBL346290 Bioactive A313326 Analogue 53
CFAMM00371879 CHEMBL183313 Bioactive AGN-PC-075G0J

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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