CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate receptor 3 ligand AGN-PC-07ZDH8 family
No. of Seeds 7 No. of Other Members 4
Family Centroid CFAMM00313946 Functional Category Bioactive
Superfamily Sphingosine 1-phosphate receptor 3 and Sphingosine 1-phosphate receptor 1 Binder Superfamily
Class Class 470

Cousin Family NamesSeedsMembers
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Sodium channel protein type 5 subunit alpha Ligand Mexiletine ... 7 74
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Alpha-1B adrenergic receptor ligand Phenylephrine analog Metho... 9 56
Histamine H3 receptor Ligand A-331440 Family 6 7
Histamine H3 receptor Ligand UCL-2138 Family 23 172
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 5 11
Sodium-dependent dopamine transporter and Sodium-dependent nor... 9 16
5-hydroxytryptamine receptor 2A Ligand C-(9h-xanthen-9-yl)-met... 3 5
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 4 0
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 8 4
Sphingosine 1-phosphate receptor 1 ligand (3S)-3-amino-5-(4-he... 1 1
NP (r)-(2-(4-isopropoxybenzyl)-4-methyl-4,5-dihydrooxazol-4-yl... 3 0


External ID

Functional Category

Molecule Name

CFAMM00313948 CHEMBL1089558 Bioactive AGN-PC-07N48P
CFAMM00313946 CHEMBL1089557 Bioactive AGN-PC-07ZDH8
CFAMM00313939 CHEMBL1092284 Bioactive AGN-PC-07ZDJD
CFAMM00313944 CHEMBL1084929 Bioactive [(2S)-2-amino-4-(4-heptoxyphenyl)-2-methylbutyl] dihydrogen phosphate
CFAMM00313943 CHEMBL1096211 Bioactive AGN-PC-07N41D
CFAMM00313942 CHEMBL1091630 Bioactive AGN-PC-00DD4J
CFAMM00313941 CHEMBL1092272 Bioactive AGN-PC-07N4OQ

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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