CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6447
Family Name 5-hydroxytryptamine receptor 6 ligand AGN-PC-0BRZ7B family
No. of Seeds 9 No. of Other Members 2
Family Centroid CFAMM00372858 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 6 Ligand SB-357134 Superfamily
Class Class 1633

Cousin Family NamesSeedsMembers
Tumor necrosis factor Inhibitor Tgaac-94 Family 6 107
D(4) dopamine receptor Ligand Sonepiprazole Family 2 6
5-hydroxytryptamine receptor 6 Ligand Sb 258585 Family 11 121
5-hydroxytryptamine receptor 6 Ligand SB-357134 Family 13 2
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 20 33
Alpha-1A adrenergic receptor Ligand Naftopidil Family 15 119
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 8 41
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
Pyruvate kinase PKLR and Pyruvate kinase PKM inhibitor AGN-PC-... 1 1
5-hydroxytryptamine receptor 6 ligand N-(3,5-dichlorophenyl)-4... 7 2
Alpha-2A adrenergic receptor and 5-hydroxytryptamine receptor ... 7 10
Bifunctional epoxide hydrolase 2 inhibitor SureCN2729784 family 3 9
5-hydroxytryptamine receptor 6 ligand 1-(4-methoxy-3-piperazin... 6 3
5-hydroxytryptamine receptor 6 ligand 8-chloro-2-(4-methoxy-3-... 4 1
5-hydroxytryptamine receptor 6 ligand 6-bromo-1-(4-methoxy-3-p... 2 0
Sigma non-opioid intracellular receptor 1 ligand N-[6-[[5-[3-(... 1 1
Neuropeptide Y receptor type 5 ligand N-[[4-[2-[7-(trifluorome... 1 1
5-hydroxytryptamine receptor 6 ligand AGN-PC-0BL6AB family 1 3
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 14
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 2 0
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 10 1
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 5 0
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 5 1
Growth hormone secretagogue receptor type 1 ligand SureCN48028... 7 0
Growth hormone secretagogue receptor type 1 ligand SureCN47962... 8 0
Growth hormone secretagogue receptor type 1 ligand SureCN48020... 3 0
D(3) dopamine receptor and D(2) dopamine receptor ligand 4-met... 3 3
72 kDa type IV collagenase and Interstitial collagenase inhibi... 2 0
Substance-P receptor ligand CP 141938 family 1 0
5-hydroxytryptamine receptor 6 ligand N-(3-bromo-2,5-dichlorop... 2 0
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 1 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 3 3
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 2 1
Histamine H3 receptor ligand 1-naphthalen-1-yl-3-[4-(3-pyrroli... 1 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 2-[3-... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00372851 CHEMBL157338 Bioactive 5,8-dimethoxy-2-(4-methoxy-3-piperazin-1-ylphenyl)sulfonyl-3,4-dihydro-1H-isoquinoline
CFAMM00372858 CHEMBL2152924 Bioactive AGN-PC-0BRZ7B
CFAMM00372857 CHEMBL2152927 Bioactive AGN-PC-0BRZ7H
CFAMM00372863 CHEMBL2152926 Bioactive AGN-PC-0BRZ7F
CFAMM00372854 CHEMBL2153063 Bioactive AGN-PC-0BRZ77
CFAMM00372853 CHEMBL2153060 Bioactive AGN-PC-0BRZ3A
CFAMM00372860 CHEMBL2152928 Bioactive AGN-PC-0BRZBB
CFAMM00372852 CHEMBL2153061 Bioactive AGN-PC-0BRZ3C
CFAMM00372859 CHEMBL2152929 Bioactive AGN-PC-0BRZ36

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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