CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM650
Family Name Histamine H3 receptor and Potassium voltage-gated channel subfamily H member 2 ligand SureCN1640184 family
No. of Seeds 3 No. of Other Members 11
Family Centroid CFAMM00314031 Functional Category Bioactive with Natural Product
Superfamily Histamine H3 receptor and 5-hydroxytryptamine receptor 7 Binder Superfamily
Class Class 2639

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Dibucaine F... 2 136
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 12 197
Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 4 42
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
Cannabinoid receptor 2 Ligand JWH-202 Family 9 172
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand WIN-5... 12 52
DNA-dependent protein kinase catalytic subunit Inhibitor 8-(1h... 3 85
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 3-(furan-3-... 3 44
Platelet-derived growth factor receptor alpha and Platelet-der... 2 13
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 14 214
Platelet-derived growth factor receptor beta and Receptor-type... 1 2
Metabotropic glutamate receptor 1 Ligand JNJ-16259685 Family 3 20
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(4-methoxyphenyl)qu... 2 11
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 9 12
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 8 12
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 7 1
Mu-type opioid receptor ligand AGN-PC-075GBK family 4 4
NS5B protein inhibitor AC1O5AET family 3 1
Serine/threonine-protein kinase pim-2 and cGMP-dependent prote... 8 1
Cytosolic phospholipase A2 inhibitor AGN-PC-00BH8R family 6 13
Sodium-dependent serotonin transporter and Alpha-1B adrenergic... 42 20
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-(1-... 3 2
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 6 159
Potassium voltage-gated channel subfamily H member 2 and 5-hyd... 2 2
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 4 4
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 1 0
Cathepsin K inhibitor N-[(2S)-4-methyl-1-[2-[4-(2-methylpropox... 4 0
CGMP-dependent protein kinase inhibitor AGN-PC-075IHL family 2 8
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL4... 6 2
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 1 0
Adenosine receptor A2b and Adenosine receptor A2a ligand SureC... 2 0
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 5 0
Cholinesterase and Acetylcholinesterase inhibitor AGN-PC-04T5L... 1 0
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 6 0
Bombesin receptor subtype-3 ligand 2-[[(E)-furan-2-ylmethylide... 2 4
Sodium-dependent serotonin transporter inhibitor SureCN5477150... 4 1
Nuclear receptor ROR-gamma and Ras-related protein Rab-9A liga... 1 0
Histamine H1 receptor and Alpha-1B adrenergic receptor ligand ... 1 4
NS5B protein inhibitor AGN-PC-0765HJ family 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00314031 CHEMBL1085326 Bioactive SureCN1640184
CFAMM00314030 CHEMBL2368734 Bioactive 6-fluoro-3-[(3R,4R)-4-fluoropiperidin-3-yl]-2-(furan-3-yl)-1H-indole
CFAMM00314028 CHEMBL1822867 Bioactive SureCN6067828

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27263 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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