CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6504
Family Name cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor 3-[2-[3-cyclopentyloxy-4-(difluoromethoxy)phenyl]propyl]-1H-imidazol-2-one family
No. of Seeds 2 No. of Other Members 25
Family Centroid CFAMM00373168 Functional Category Bioactive
Superfamily Alpha-1A adrenergic receptor and Alpha-2A adrenergic receptor Binder Superfamily 2
Class Class 1096

Cousin Family NamesSeedsMembers
Cytochrome P450 3A4 Inhibitor SK&F-96365 Family 2 26
Beta-1 adrenergic receptor ligand 1-[4-[2-(5-bromo-1H-imidazol... 3 8
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
Glutaminyl-peptide cyclotransferase inhibitor AGN-PC-077IHD fa... 1 1
Thromboxane A2 receptor and Thromboxane-A synthase ligand 5-[(... 1 0
Alpha-2A adrenergic receptor and Alpha-1A adrenergic receptor ... 1 3
Alpha-1A adrenergic receptor ligand AGN-PC-0793UT family 3 3
Glutaminyl-peptide cyclotransferase inhibitor thioamide deriv.... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00373168 CHEMBL157812 Bioactive 3-[2-[3-cyclopentyloxy-4-(difluoromethoxy)phenyl]propyl]-1H-imidazol-2-one
CFAMM00373177 CHEMBL434092 Bioactive AGN-PC-00CAP6

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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