CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6526
Family Name Methionine--tRNA ligase inhibitor 2-[3-[(5-bromo-2-ethoxy-3-methylphenyl)methylamino]propylamino]-1H-quinolin-4-one family
No. of Seeds 9 No. of Other Members 11
Family Centroid CFAMM00373324 Functional Category Bioactive
Superfamily Methionine--tRNA ligase and Methionine--tRNA ligase, cytoplasmic Binder Superfamily
Class Class 4447

Cousin Family NamesSeedsMembers
Epidermal growth factor receptor Ligand Gefitinib Family 26 600
Reverse transcriptase Inhibitor Etravirine Family 1 2
Tyrosine kinase Inhibitor PKI166 Family 17 198
Peptide deformylase, mitochondrial Inhibitor 5-(4-methoxypheno... 5 61
Prostaglandin D2 receptor ligand 3-[2-methoxy-6-[2-(4-methoxyp... 2 12
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL13704... 1 7
Methionine--tRNA ligase inhibitor 2-[3-[(2-ethoxy-5-iodo-3-met... 9 32
Methionine--tRNA ligase inhibitor SureCN7818675 family 7 14
Methionine--tRNA ligase inhibitor 2-[3-[(3-bromo-2-ethoxy-5-me... 2 1
Methionine--tRNA ligase, cytoplasmic and Methionine--tRNA liga... 8 6
Methionine--tRNA ligase inhibitor SureCN7818124 family 1 9
Methionine--tRNA ligase inhibitor SureCN8172942 family 3 1
Prostaglandin D2 receptor ligand 2-[3-[2-methoxy-6-[2-(4-metho... 4 12
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 2 5
Prostaglandin D2 receptor ligand 1-[3-[2-methoxy-6-[2-(4-metho... 6 16
Adenosine receptor A3 ligand AGN-PC-08WSLM family 5 22
Inhibitor of nuclear factor kappa-B kinase subunit beta inhibi... 8 3
Dihydrofolate reductase inhibitor 7-(5-chloro-2-ethoxyphenyl)-... 2 1
Methionine--tRNA ligase inhibitor 2-[3-[(3,5-dibromo-2-ethoxyp... 2 1
Xanthine dehydrogenase/oxidase inhibitor 5-(2-amino-4-oxo-1H-p... 8 30
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 2
Adenosine receptor A1 and Adenosine receptor A2a ligand 7-meth... 2 0
Methionine--tRNA ligase inhibitor AGN-PC-075EJD family 2 1
Epidermal growth factor receptor ligand 4-Anilinoquinazoline d... 2 0
1-acyl-sn-glycerol-3-phosphate acyltransferase beta inhibitor ... 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00373324 CHEMBL422699 Bioactive 2-[3-[(5-bromo-2-ethoxy-3-methylphenyl)methylamino]propylamino]-1H-quinolin-4-one
CFAMM00373316 CHEMBL368020 Bioactive 2-[3-[(3-bromo-2-ethoxy-5-methoxyphenyl)methylamino]propylamino]-1H-quinazolin-4-one
CFAMM00373330 CHEMBL160597 Bioactive 2-[3-[(3-bromo-2-ethoxy-5-iodophenyl)methylamino]propylamino]-1H-quinolin-4-one
CFAMM00373314 CHEMBL157996 Bioactive 2-[3-[(5-bromo-2-ethoxy-3-iodophenyl)methylamino]propylamino]-1H-quinolin-4-one
CFAMM00373313 CHEMBL160506 Bioactive 2-[3-[(3,5-dibromo-2-ethoxyphenyl)methylamino]propylamino]-1H-quinolin-4-one
CFAMM00373320 CHEMBL160161 Bioactive 2-[3-[(3-bromo-2-ethoxy-5-methoxyphenyl)methylamino]propylamino]-1H-quinolin-4-one
CFAMM00373319 CHEMBL159035 Bioactive 5-bromo-2-ethoxy-3-[[3-[(4-oxo-1H-quinolin-2-yl)amino]propylamino]methyl]benzonitrile
CFAMM00373331 CHEMBL158501 Bioactive 3-bromo-4-ethoxy-5-[[3-[(4-oxo-1H-quinolin-2-yl)amino]propylamino]methyl]benzonitrile
CFAMM00373317 CHEMBL160300 Bioactive 2-[3-[(3-bromo-2-ethoxy-5-methylphenyl)methylamino]propylamino]-1H-quinolin-4-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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