CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6531
Family Name Methionine--tRNA ligase inhibitor SureCN7818675 family
No. of Seeds 7 No. of Other Members 14
Family Centroid CFAMM00373352 Functional Category Bioactive
Superfamily Epidermal growth factor receptor and Receptor tyrosine-protein kinase erbB-2 Binder Superfamily
Class Class 2955

Cousin Family NamesSeedsMembers
Epidermal growth factor receptor Ligand Gefitinib Family 26 600
Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Inhibi... 3 64
Melanin-concentrating hormone receptor 1 Ligand ADS-102891 Family 6 51
Methionine--tRNA ligase inhibitor 2-[3-[(2-ethoxy-5-iodo-3-met... 9 32
Methionine--tRNA ligase inhibitor 2-[3-[(5-bromo-2-ethoxy-3-me... 9 11
Methionine--tRNA ligase inhibitor 2-[3-[(3-bromo-2-ethoxy-5-me... 2 1
Methionine--tRNA ligase inhibitor 2-({3-[(3,5-Dichlorobenzyl)a... 5 7
Methionine--tRNA ligase inhibitor SureCN7818124 family 1 9
Methionine--tRNA ligase inhibitor SureCN8172942 family 3 1
Fatty-acid amide hydrolase 1 inhibitor (1R)-2-[[6-(3-chloro-4-... 1 4
Dihydrofolate reductase inhibitor 7-(5-chloro-2-ethoxyphenyl)-... 2 1
Methionine--tRNA ligase inhibitor 2-[3-[(3,5-dibromo-2-ethoxyp... 2 1
Bifunctional dihydrofolate reductase-thymidylate synthase inhi... 3 5
1-acyl-sn-glycerol-3-phosphate acyltransferase beta inhibitor ... 1 2
1-acyl-sn-glycerol-3-phosphate acyltransferase beta inhibitor ... 1 1
1-acyl-sn-glycerol-3-phosphate acyltransferase beta inhibitor ... 1 0


External ID

Functional Category

Molecule Name

CFAMM00373361 CHEMBL159068 Bioactive SureCN8228744
CFAMM00373354 CHEMBL158904 Bioactive SureCN8189833
CFAMM00373352 CHEMBL160892 Bioactive SureCN7818675
CFAMM00373358 CHEMBL158051 Bioactive 2-[3-[(6,8-dichloro-3,4-dihydro-2H-chromen-4-yl)amino]propylamino]-1H-quinolin-4-one
CFAMM00373350 CHEMBL183022 Bioactive 2-[3-[(3,5-dichloro-2-ethoxyphenyl)methylamino]propylamino]-1H-quinazolin-4-one
CFAMM00373349 CHEMBL158513 Bioactive 2-[3-[(5-chloro-2-ethoxy-3-methylphenyl)methylamino]propylamino]-1H-quinolin-4-one
CFAMM00373363 CHEMBL158678 Bioactive 2-[3-[(3-chloro-2-ethoxy-5-methoxyphenyl)methylamino]propylamino]-1H-quinolin-4-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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