CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6537
Family Name Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptamine receptor 1A ligand AGN-PC-03OYBF family
No. of Seeds 18 No. of Other Members 12
Family Centroid CFAMM00311830 Functional Category Bioactive
Superfamily Sigma non-opioid intracellular receptor 1 and Cytochrome P450 2D6 Binder Superfamily
Class Class 32

Cousin Family NamesSeedsMembers
Muscarinic acetylcholine receptor M5 ligand phenothiazine deri... 8 37
Histamine H1 receptor ligand phenothiazine derivative Mequitaz... 3 2
5-hydroxytryptamine receptor Ligand Lu AA21004 Family 13 39
5-hydroxytryptamine receptor 6 Ligand 4-(4-benzenesulfonamidop... 4 5
5-hydroxytryptamine receptor 2A Ligand Cinanserin Family 3 27
D(2) dopamine receptor Ligand 7-(2-dipropylamino-ethyl)-3h-ben... 1 4
Sigma non-opioid intracellular receptor 1 and Histamine H1 rec... 5 9
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 10
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 2
Sigma non-opioid intracellular receptor 1 ligand 3-[4-(azepan-... 8 1
Sigma non-opioid intracellular receptor 1 ligand 3-[3-(azepan-... 4 4
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00373406 CHEMBL2414423 Bioactive 3-[3-(azepan-1-yl)propyl]-6-butyl-1,3-benzothiazol-2-one
CFAMM00373405 CHEMBL2414424 Bioactive 3-[4-(azepan-1-yl)butyl]-6-butyl-1,3-benzothiazol-2-one;hydrochloride
CFAMM00373392 CHEMBL274699 Bioactive SureCN12359955
CFAMM00373398 CHEMBL2414419 Bioactive 3-[3-(azepan-1-yl)propyl]-6-propyl-1,3-benzothiazol-2-one
CFAMM00373411 CHEMBL2414421 Bioactive 3-[5-(azepan-1-yl)pentyl]-6-propyl-1,3-benzothiazol-2-one
CFAMM00373410 CHEMBL272899 Bioactive 3-[2-(azepan-1-yl)ethyl]-6-propyl-1,3-benzothiazol-2-one
CFAMM00373390 CHEMBL2181924 Bioactive 3-[2-(azepan-1-yl)ethyl]-6-(3-fluoropropyl)-1,3-benzothiazol-2-one
CFAMM00373402 CHEMBL61818 Bioactive 3-methyl-6-[4-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]butyl]-1,3-benzothiazol-2-one
CFAMM00373389 CHEMBL418499 Bioactive 3-methyl-6-[2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]ethyl]-1,3-benzothiazol-2-one
CFAMM00373408 CHEMBL2414420 Bioactive 3-[4-(azepan-1-yl)butyl]-6-propyl-1,3-benzothiazol-2-one
CFAMM00373407 CHEMBL2414422 Bioactive 3-[6-(azepan-1-yl)hexyl]-6-propyl-1,3-benzothiazol-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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