CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6546
Family Name Survival motor neuron protein inhibitor CHEMBL1581561 family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00373443 Functional Category Bioactive with Natural Product
Superfamily Toll-like receptor 7 and Adenosine receptor A2a Binder Superfamily
Class Class 925

Cousin Family NamesSeedsMembers
Neuropeptide Y receptor type 5 Ligand CGP71683A Family 5 74
Transient receptor potential cation channel subfamily V member... 15 457
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 35 270
GDC-0349 family 44 77
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 8 55
5-hydroxytryptamine receptor 2B Ligand MT-500 Family 8 39
Epidermal growth factor receptor and Receptor tyrosine-protein... 11 138
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 32
Peptide deformylase, mitochondrial Inhibitor 5-phenethyl-quina... 5 14
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Scytalone dehydratase Inhibitor Isoquinolin-1-yl-(3-phenyl-pro... 4 9
Epidermal growth factor receptor Ligand Benzo[g]quinazolin-4-y... 5 3
Histamine H3 receptor Ligand 2-(4-isopropyl-piperazin-1-yl)-qu... 17 29
Cyclin-dependent kinase 2 and Mitogen-activated protein kinase... 7 30
Adenosine receptor A3 Ligand 1-(2-(diethylamino)quinazolin-4-y... 2 9
Mitogen-activated protein kinase 14 and Tyrosine-protein kinas... 3 9
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2,6... 22 18
Cathepsin K Inhibitor 4-phenyl-6-propylpyrimidine-2-carbonitri... 6 10
Oestrogen receptor Ligand 4-benzyl-2,6-diisobutylamino-pyrimid... 5 37
Histamine H4 receptor Ligand A-943931 Family 14 11
Arachidonate 5-lipoxygenase Inhibitor Methyl 2-(benzylamino)-1... 3 10
Sodium-dependent serotonin transporter Inhibitor 6-chloro-2-pi... 5 35
Sodium channel protein type 1 subunit alpha and Sodium channel... 10 14
Amine oxidase [flavin-containing] A Inhibitor 3-benzyl-n-(2-mo... 2 3
Acetylcholinesterase Inhibitor N-benzyl-2-morpholinopyrimidin-... 6 16
Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... 62 27
Cathepsin K and Potassium voltage-gated channel subfamily H me... 3 1
Histamine H4 receptor ligand 2-[[6-iodo-2-(4-methylpiperazin-1... 4 2
Bifunctional dihydrofolate reductase-thymidylate synthase inhi... 2 12
Glutamate receptor ionotropic, NMDA 2D and Glutamate receptor ... 3 3
Neuropeptide Y receptor type 5 ligand SureCN8898853 family 2 3
Growth hormone secretagogue receptor type 1 ligand SureCN62436... 8 6
Histamine H4 receptor and Histamine H3 receptor ligand 7-cyclo... 2 0
Histamine H4 receptor ligand 2-[[6-chloro-2-(4-methylpiperazin... 7 2
P2Y purinoceptor 14 inhibitor AGN-PC-0A9S8H family 3 2
Corticotropin-releasing factor receptor 1 ligand 5-N,5-N-bis(c... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00373444 CHEMBL276530 Bioactive AGN-PC-03SXJ4

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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