CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6565
Family Name Neuronal acetylcholine receptor subunit alpha-4 and Neuronal acetylcholine receptor subunit beta-2 ligand SureCN6584728 family
No. of Seeds 3 No. of Other Members 7
Family Centroid CFAMM00373563 Functional Category Bioactive with Natural Product
Superfamily Neuronal acetylcholine receptor subunit beta-2 and Neuronal acetylcholine receptor subunit alpha-4 Binder Superfamily 4
Class Class 2009

Cousin Family NamesSeedsMembers
Nicotinic acetylcholine receptor Ligand AZD0328 Family 11 97
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor Lig... 9 115
Nicotinic acetylcholine receptor Ligand Dianicline Family 6 13
Fatty-acid amide hydrolase 1 Inhibitor 1-(5-(pyridin-2-yl)oxaz... 10 142
Cytochrome P450 3A4 Inhibitor 3-(5-((methylthio)methyl)furan-2... 4 14
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand WIN-5... 12 52
DNA-dependent protein kinase catalytic subunit Inhibitor 8-(1h... 3 85
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 4 35
RAC-gamma serine/threonine-protein kinase Inhibitor A-443654 F... 67 59
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 14 214
Cytochrome P450 11B1, mitochondrial Inhibitor 5-(6-methoxynaph... 7 4
Cannabinoid receptor 1 Ligand 1-(2-morpholinoethyl)-1h-indol-3... 8 46
Acetylcholinesterase Inhibitor Lysicamine Family 2 8
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 22 57
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 4 20
Histamine H3 receptor and Potassium voltage-gated channel subf... 5 2
Histone deacetylase 1 and Histone deacetylase 2 inhibitor AGN-... 4 15
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 8 8
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 11 4
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 2 4
Histamine H3 receptor ligand SureCN2784306 family 5 3
Cytochrome P450 11B2, mitochondrial and Cytochrome P450 11B1, ... 9 7
Fatty-acid amide hydrolase 1 inhibitor methyl 6-[2-[3-(4-pheny... 8 5
Serine/threonine-protein kinase B-raf inhibitor furan-based co... 6 3
Fatty-acid amide hydrolase 1 and Liver carboxylesterase 1 inhi... 2 2
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 15 4
Sodium-dependent serotonin transporter inhibitor AGN-PC-075G9A... 3 2
Sodium-dependent serotonin transporter and Sodium-dependent do... 2 0
Neuronal acetylcholine receptor subunit alpha-2 and Neuronal a... 6 1
Neuronal acetylcholine receptor subunit alpha-7 and Potassium ... 1 0
Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... 5 0
Peroxisome proliferator-activated receptor gamma and Peroxisom... 10 5
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 3 3
CGMP-dependent protein kinase inhibitor AGN-PC-075IHL family 2 8
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 2 3
Mu-type opioid receptor ligand N-[(5-methylfuran-2-yl)methyl]-... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00373561 CHEMBL159136 Bioactive 3-(1-benzofuran-2-yl)-5-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]pyridine
CFAMM00373563 CHEMBL158331 Bioactive SureCN6584728
CFAMM00373562 CHEMBL158944 Bioactive 2-[5-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]pyridin-3-yl]benzaldehyde

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27751 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543