CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6575
Family Name 5-hydroxytryptamine receptor 7 and 5-hydroxytryptamine receptor 1A ligand SureCN2469726 family
No. of Seeds 3 No. of Other Members 7
Family Centroid CFAMM00314080 Functional Category Bioactive
Superfamily Retinal dehydrogenase 1 and Nuclear receptor ROR-gamma Binder Superfamily 2
Class Class 1997

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Etoricoxib Family 2 99
Histamine H1 receptor Ligand Pheniramine Family 10 380
Platelet-derived growth factor receptor alpha and Platelet-der... 5 48
Cytochrome P450 3A4 Inhibitor 3-(3-methylthiophen-2-yl)pyridin... 5 27
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 7 16
Mitogen-activated protein kinase 14 Inhibitor 4-(2-ethyl-4-m-t... 14 41
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 14 19
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-264... 6 32
Prostaglandin G/H synthase 1 Inhibitor 1-(4-aminosulfonylpheny... 3 18
Histamine H3 receptor Ligand ST-1025 Family 2 22
Metabotropic glutamate receptor 5 Ligand 5-((6-methylpyridin-2... 14 22
Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... 62 27
Histamine H3 receptor and Potassium voltage-gated channel subf... 6 20
Histamine H3 receptor and Potassium voltage-gated channel subf... 6 14
5-hydroxytryptamine receptor 6 ligand CHEMBL1950756 family 8 8
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 4 8
D(2) dopamine receptor and D(3) dopamine receptor ligand 8-chl... 6 3
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 3 1
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor lig... 2 4
5-hydroxytryptamine receptor 2A and Alpha-1B adrenergic recept... 8 6
Amyloid beta A4 protein and Luciferin 4-monooxygenase inhibito... 11 46
5-hydroxytryptamine receptor 1A and Alpha-2C adrenergic recept... 2 2
Amyloid beta A4 protein inhibitor SureCN2465837 family 4 2
Voltage-dependent L-type calcium channel subunit alpha-1C and ... 2 1
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 1 0
Muscleblind-like protein 1 and Huntingtin inhibitor AC1LYOWT f... 1 0
Indoles Metabolite Sinalbin B Family 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00373598 CHEMBL158402 Bioactive 2-(6-cyclohexylpyridin-2-yl)sulfanyl-N,N-dimethylethanamine
CFAMM00373596 CHEMBL1762480 Bioactive 2-[(1R)-3-amino-1-phenylpropyl]sulfanyl-6-methylpyridine-3-carbonitrile;(E)-but-2-enedioic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27522 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543