CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6586
Family Name Histamine H3 receptor ligand N-[(2R)-1-[4-[3-[4-[5-(cyclopentylmethyl)-1,2,4-oxadiazol-3-yl]-3-fluorophenoxy]propyl]piperazin-1-yl]-1-oxopropan-2-yl]-2-fluorobenzamide family
No. of Seeds 27 No. of Other Members 2
Family Centroid CFAMM00362415 Functional Category Bioactive
Superfamily Histamine H3 receptor and Cellular tumor antigen p53 Binder Superfamily
Class Class 1632

Cousin Family NamesSeedsMembers
Adenosine receptor A1 and Adenosine receptor A2a Ligand SB-298... 53 320
Adenosine receptor A1 and Adenosine receptor A2a ligand 2-[4-[... 12 15
Adenosine receptor A2b and Adenosine receptor A1 ligand SureCN... 52 12
Adenosine receptor A2b and Adenosine receptor A1 ligand MRS 17... 10 0
Histamine H3 receptor ligand N-[(2R)-1-[4-[3-[4-(5-ethyl-1,2,4... 25 61
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL15310... 1 11
Histamine H3 receptor ligand N-[(2R)-1-[4-[3-[3-fluoro-4-(5-ph... 10 2
Histamine H3 receptor ligand SureCN7248940 family 20 0
Histamine H3 receptor ligand SureCN7252761 family 3 0
Histamine H3 receptor ligand SureCN7251693 family 3 1
Adenosine receptor A1 and Adenosine receptor A3 ligand SureCN5... 3 1
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 3 0
Adenosine receptor A1 and Adenosine receptor A2b ligand (2,5-d... 2 0
5-hydroxytryptamine receptor 1B and Sodium- and chloride-depen... 1 5
Androgen receptor ligand 4-[4,4-dimethyl-2-oxo-1-[(5-phenyl-1,... 1 0
Sodium- and chloride-dependent glycine transporter 2 and Sodiu... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00373648 CHEMBL350649 Bioactive SureCN7249399
CFAMM00373646 CHEMBL350385 Bioactive N-[(2R)-1-[4-[3-[4-[5-(cyclopentylmethyl)-1,2,4-oxadiazol-3-yl]-3-fluorophenoxy]propyl]-1,4-diazepan-1-yl]-1-oxopropan-2-yl]-4-methoxybenzamide
CFAMM00373642 CHEMBL161138 Bioactive 4-cyano-N-[(2R)-1-[4-[3-[4-[5-(cyclopentylmethyl)-1,2,4-oxadiazol-3-yl]-3-fluorophenoxy]propyl]piperazin-1-yl]-1-oxopropan-2-yl]benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26832 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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