CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6588
Family Name Survival motor neuron protein and Microtubule-associated protein tau inhibitor CHEMBL1601322 family
No. of Seeds 2 No. of Other Members 14
Family Centroid CFAMM00373677 Functional Category Bioactive with Natural Product
Superfamily DNA ligase Inhibitor 7-(4-methoxyphenyl)pteridine-2,4-diol Superfamily
Class Class 227

Cousin Family NamesSeedsMembers
Adenosine receptor A2a Ligand KW-6002 Family 18 195
GP-531 family 1 33
5-hydroxytryptamine receptor 1A Ligand P-MPPI Family 33 81
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 6 14
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN1... 6 16
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN8... 17 3
Adenosine receptor A1 and Adenosine receptor A2b ligand 3-meth... 7 19
Adenosine receptor A1 and Adenosine receptor A2a ligand 2-[4-[... 12 15
Adenosine receptor A2b and Adenosine receptor A1 ligand SureCN... 52 12
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 14
Prelamin-A/C inhibitor CHEMBL1501476 family 1 2
Fatty-acid amide hydrolase 1 inhibitor [4-(4-methoxyphenyl)pip... 1 1
5-hydroxytryptamine receptor 2A and Sodium-dependent serotonin... 3 14
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 7
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 4 2
Corticotropin-releasing factor receptor 1 ligand AGN-PC-00G4OY... 3 0
Corticotropin-releasing factor receptor 1 ligand Pyridopyrazin... 2 1
Corticotropin-releasing factor receptor 1 ligand AGN-PC-009TSL... 3 3
C-X-C chemokine receptor type 3 ligand 3-amino-6-chloro-5-[(3S... 1 3
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL2... 13 2
5-hydroxytryptamine receptor 1A and D(4) dopamine receptor lig... 1 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN8... 10 0
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 2
cGMP-specific 3',5'-cyclic phosphodiesterase and Calcium/calmo... 2 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 2 1
P2X purinoceptor 7 inhibitor (7R)-1-[(3,4-difluorophenyl)methy... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00373668 CHEMBL2112360 Bioactive 8-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethylamino]-1,3-dimethylpurino[7,8-a]pyrimidine-2,4-dione
CFAMM00373658 CHEMBL328292 Bioactive 9-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-1,3-dimethyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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