CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM659
Family Name Beta-2 adrenergic receptor and Beta-1 adrenergic receptor ligand acetic acid;1-ethyl-3-[3-[4-[6-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl]amino]hexoxy]butyl]phenyl]urea family
No. of Seeds 20 No. of Other Members 7
Family Centroid CFAMM00314096 Functional Category Bioactive
Superfamily Beta-1 adrenergic receptor and Beta-2 adrenergic receptor Binder Superfamily
Class Class 287

Cousin Family NamesSeedsMembers
Alpha-1 adrenergic receptor ligand arylethanolamine derivative... 4 37
Beta-2 adrenergic receptor Ligand Formoterol Family 16 63
Beta-2 adrenergic receptor ligand catecholamine Salbutamol Family 10 90
Beta-2 adrenergic receptor Ligand Procaterol Family 7 42
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 1 1
Muscarinic acetylcholine receptor M3 and Beta-2 adrenergic rec... 5 0
Beta-2 adrenergic receptor and Beta-3 adrenergic receptor liga... 3 0
Beta-2 adrenergic receptor ligand 4-[2-[2-[4-[[2-(4-chlorophen... 1 1
Beta-2 adrenergic receptor ligand 4-[2-[2-[4-[[2-(2,5-dimethox... 1 1
Acyl-CoA:cholesterol acyltransferase inhibitor SureCN9614694 f... 3 14


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00314092 CHEMBL1814271 Bioactive acetic acid;3-[3-[4-[6-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl]amino]hexoxy]butyl]phenyl]-5,5-dimethylimidazolidine-2,4-dione
CFAMM00314105 CHEMBL1814267 Bioactive acetic acid;1-[3-[4-[6-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl]amino]hexoxy]butyl]phenyl]pyrimidine-2,4-dione
CFAMM00314091 CHEMBL1814276 Bioactive acetic acid;2-[3-[3-[4-[6-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl]amino]hexoxy]butyl]phenyl]-2,5-dioxoimidazolidin-1-yl]acetamide
CFAMM00314104 CHEMBL1814269 Bioactive acetic acid;3-[4-[4-[6-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl]amino]hexoxy]butyl]phenyl]imidazolidine-2,4-dione
CFAMM00314097 CHEMBL1835855 Bioactive acetic acid;1-cyclohexyl-3-[3-[4-[6-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl]amino]hexoxy]butyl]phenyl]urea
CFAMM00314090 CHEMBL1814277 Bioactive 3-[3-[4-[6-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl]amino]hexoxy]butyl]phenyl]-1H-pyrimidine-2,4-dione
CFAMM00314103 CHEMBL1814268 Bioactive acetic acid;3-[3-[4-[6-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl]amino]hexoxy]butyl]phenyl]imidazolidine-2,4-dione
CFAMM00314096 CHEMBL1835854 Bioactive acetic acid;1-ethyl-3-[3-[4-[6-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl]amino]hexoxy]butyl]phenyl]urea
CFAMM00314109 CHEMBL1835856 Bioactive acetic acid;1-ethyl-3-[4-[4-[6-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl]amino]hexoxy]butyl]phenyl]urea
CFAMM00314095 CHEMBL1814272 Bioactive acetic acid;1-[3-[4-[6-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl]amino]hexoxy]butyl]phenyl]imidazolidine-2,4-dione
CFAMM00314108 CHEMBL1835862 Bioactive acetic acid;[3-[4-[6-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl]amino]hexoxy]butyl]-5-methylphenyl]urea
CFAMM00314088 CHEMBL1814278 Bioactive acetic acid;3-[3-[4-[6-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl]amino]hexoxy]butyl]phenyl]-1H-pyrimidine-2,4-dione
CFAMM00314101 CHEMBL1814280 Bioactive acetic acid;2-[[3-[4-[6-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl]amino]hexoxy]butyl]phenyl]carbamoylamino]acetic acid
CFAMM00314107 CHEMBL1835860 Bioactive acetic acid;N-cyclopentyl-2-[[3-[4-[6-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl]amino]hexoxy]butyl]phenyl]carbamoylamino]acetamide
CFAMM00314100 CHEMBL1835859 Bioactive formic acid;2-[[3-[4-[6-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl]amino]hexoxy]butyl]phenyl]carbamoylamino]acetamide
CFAMM00314087 CHEMBL1814279 Bioactive 2-[[3-[4-[6-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl]amino]hexoxy]butyl]phenyl]carbamoylamino]acetic acid
CFAMM00314093 CHEMBL1814270 Bioactive 3-[2-[4-[6-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl]amino]hexoxy]butyl]phenyl]imidazolidine-2,4-dione
CFAMM00314106 CHEMBL1835861 Bioactive acetic acid;[3-[4-[6-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl]amino]hexoxy]butyl]-5-(trifluoromethyl)phenyl]urea
CFAMM00314099 CHEMBL1835853 Bioactive acetic acid;[3-[4-[6-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl]amino]hexoxy]butyl]phenyl]urea

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27396 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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