CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6594
Family Name Bifunctional dihydrofolate reductase-thymidylate synthase inhibitor SureCN7116675 family
No. of Seeds 11 No. of Other Members 12
Family Centroid CFAMM00373720 Functional Category Bioactive
Superfamily Bifunctional dihydrofolate reductase-thymidylate synthase Binder Superfamily
Class Class 4464

Cousin Family NamesSeedsMembers
Acyl-CoA desaturase Inhibitor Isoxyl Family 5 62
C-C chemokine receptor type 1 Ligand BX-471 Family 10 67
Alpha-1A adrenergic receptor and D(2) dopamine receptor Ligand... 5 49
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
Bifunctional dihydrofolate reductase-thymidylate synthase inhi... 2 0
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 4 19
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 6 3
Fatty-acid amide hydrolase 1 inhibitor 4-[[3-(4-chlorophenoxy)... 1 0
Bifunctional epoxide hydrolase 2 inhibitor SureCN3178516 family 3 1
Histamine H3 receptor and Histamine receptor H3 ligand 1-(3,5-... 1 0
Neuropeptide Y receptor type 5 ligand 1-[1-(4-fluorophenyl)pro... 2 8
Melanin-concentrating hormone receptor 1 and D(2) dopamine rec... 1 0
Dihydrofolate reductase inhibitor 4-[[4-(4,6-diamino-2,2-dimet... 1 1
D(2) dopamine receptor and D(3) dopamine receptor ligand 1-(3-... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00373720 CHEMBL161117 Bioactive SureCN7116675
CFAMM00373726 CHEMBL354011 Bioactive AGN-PC-00FEBE
CFAMM00373732 CHEMBL348151 Bioactive 1-(3-chlorophenyl)-2-[3-[3-(trifluoromethyl)phenoxy]phenyl]-2H-1,3,5-triazine-4,6-diamine
CFAMM00373718 CHEMBL161034 Bioactive AGN-PC-006DXK
CFAMM00373730 CHEMBL161451 Bioactive AGN-PC-00A2G0
CFAMM00373723 CHEMBL346982 Bioactive AGN-PC-008WX6
CFAMM00373716 CHEMBL158570 Bioactive 2-[3-(4-chlorophenoxy)phenyl]-1-(3-chlorophenyl)-2H-1,3,5-triazine-4,6-diamine
CFAMM00373729 CHEMBL352195 Bioactive 2-[3-(4-chlorophenoxy)phenyl]-1-(4-chlorophenyl)-2H-1,3,5-triazine-4,6-diamine
CFAMM00373722 CHEMBL159032 Bioactive SureCN7119153
CFAMM00373715 CHEMBL161757 Bioactive AGN-PC-007D5F
CFAMM00373721 CHEMBL351099 Bioactive 1-(4-chlorophenyl)-2-(3-phenylmethoxyphenyl)-2H-1,3,5-triazine-4,6-diamine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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