CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM66
Family Name Trypsin-1 and Prothrombin inhibitor (3S,3aR,6aS)-3-benzyl-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-one family
No. of Seeds 2 No. of Other Members 23
Family Centroid CFAMM00306606 Functional Category Bioactive with Human Metabolite & Natural Product
Superfamily Trypsin-1 and Prothrombin Binder Superfamily
Class Class 3067

Cousin Family NamesSeedsMembers
Alpha-2 adrenergic receptor ligand opiate Meperidine Family 13 76
Cyclooxygenase Inhibitor Flurbiprofen Family 18 294
CPI-613 family 4 35
Carboxypeptidase B2 Inhibitor Dl-benzylsuccinic Acid Family 1 11
C-X-C chemokine receptor type 1 and C-X-C chemokine receptor t... 2 53
Calcium-activated potassium channel subunit alpha-1 Ligand Tri... 1 10
Collagenase 3 and Macrophage metalloelastase Inhibitor 5-(4'-c... 4 43
Chymotrypsinogen B inhibitor (6E)-6-(iodomethylidene)-4-phenyl... 1 1
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 9
Sodium-dependent dopamine transporter inhibitor AGN-PC-074TA8 ... 2 5
Carboxylic Acids and Derivatives Metabolite 3-Acetoxy-3-methyl... 2 0
Phenylpropenes Metabolite alpha-Amylcinnamyl acetate Family 3 3
Putative NP ZINC06763537 Family 6 4
Putative NP ZINC02930279 Family 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00306622 CHEMBL102081 Bioactive (3R,3aR,6aS)-3-benzyl-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-one
CFAMM00306606 CHEMBL101030 Bioactive (3S,3aR,6aS)-3-benzyl-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27518 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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