CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6623
Family Name Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor ionotropic, NMDA 2B ligand SureCN4624599 family
No. of Seeds 4 No. of Other Members 6
Family Centroid CFAMM00373907 Functional Category Bioactive
Superfamily Alpha adrenergic receptor Ligand Tolazoline Superfamily
Class Class 45

Cousin Family NamesSeedsMembers
Beta adrenergic receptor Ligand Bethanidine Family 2 22
Voltage-dependent T-type calcium channel subunit alpha-1H liga... 10 397
AMP-activated protein kinase Inhibitor Phenformin Family 5 14
Alpha adrenergic receptor Ligand Tolazoline Family 7 51
C-X-C chemokine receptor type 4 Ligand AMD-3100 Family 3 6
Alpha-2A adrenergic receptor Ligand Brl 44408 Family 1 0
Bifunctional epoxide hydrolase 2 Inhibitor 1-cyclohexyl-3-phen... 3 12
5-hydroxytryptamine receptor 1D and Alpha-1A adrenergic recept... 3 22
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
Amine oxidase [flavin-containing] B Inhibitor 2-(4-chloropheny... 2 8
Nitric oxide synthase, brain Inhibitor 1-(benzhydrylamino)etha... 1 4
Nitric oxide synthase, inducible and Nuclear factor NF-kappa-B... 1 2
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 2 3
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 5 1
Glutamate receptor ionotropic, NMDA 2B ligand N'-[(3,5-dimethy... 1 1
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 9 12
Potassium voltage-gated channel subfamily H member 2 ligand Su... 1 0
Retinal dehydrogenase 1 and Nuclear receptor ROR-gamma ligand ... 2 1
11,13-dihydroisoindolo[2,1-b][2,4]benzodiazepin-12-ium-6-amine... 1 0


External ID

Functional Category

Molecule Name

CFAMM00373907 CHEMBL160027 Bioactive SureCN4624599
CFAMM00373906 CHEMBL159453 Bioactive SureCN4625964
CFAMM00373909 CHEMBL348727 Bioactive SureCN4625967
CFAMM00373908 CHEMBL158874 Bioactive SureCN3029548

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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