CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6667
Family Name Methionine--tRNA ligase inhibitor 2-({3-[(3,5-Dichlorobenzyl)amino]propyl}amino)quinolin-4(1h)-One family
No. of Seeds 5 No. of Other Members 7
Family Centroid CFAMM00374142 Functional Category Bioactive
Superfamily Methionine--tRNA ligase and Methionine--tRNA ligase, cytoplasmic Binder Superfamily
Class Class 4447

Cousin Family NamesSeedsMembers
Adenosine receptor A1 and Adenosine receptor A2a ligand NSC658... 8 54
Methionine--tRNA ligase inhibitor 2-[3-[(2-ethoxy-5-iodo-3-met... 9 32
Methionine--tRNA ligase inhibitor SureCN7818675 family 7 14
Methionine--tRNA ligase, cytoplasmic and Methionine--tRNA liga... 8 6
Methionine--tRNA ligase inhibitor SureCN7818124 family 1 9
Methionine--tRNA ligase inhibitor SureCN8172942 family 3 1
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-09Q7W... 7 3
Fatty-acid amide hydrolase 1 inhibitor (1R)-2-[[6-(3-chloro-4-... 1 4
Poly [ADP-ribose] polymerase 1 inhibitor 4-[1-[3-(4-oxo-1H-qui... 1 3
Serine/threonine-protein kinase Chk1 inhibitor 6-chloro-3-(1,3... 4 2
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 3 10
Thymidylate synthase inhibitor 3-(methylamino)-5,6-dihydro-4H-... 2 19
Serine/threonine-protein kinase Chk2 inhibitor (6E)-4-fluoro-6... 3 6
Inhibitor of nuclear factor kappa-B kinase subunit beta inhibi... 2 8
Transient receptor potential cation channel subfamily V member... 4 6


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00374137 CHEMBL159217 Bioactive TCMDC-139485
CFAMM00374143 CHEMBL162534 Bioactive SureCN7818202
CFAMM00374142 CHEMBL161663 Bioactive 2-({3-[(3,5-Dichlorobenzyl)amino]propyl}amino)quinolin-4(1h)-One
CFAMM00374140 CHEMBL160784 Bioactive 2-[3-[(2,5-dichlorophenyl)methylamino]propylamino]-1H-quinolin-4-one
CFAMM00374139 CHEMBL160841 Bioactive 2-[3-[(2,3,5-trichlorophenyl)methylamino]propylamino]-1H-quinolin-4-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

25240 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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