CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6671
Family Name Purine nucleoside phosphorylase inhibitor 2-amino-6-(thiophen-3-ylmethyl)-1,7-dihydropyrrolo[3,2-d]pyrimidin-4-one family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00374175 Functional Category Bioactive
Superfamily Purine nucleoside phosphorylase and Menin Binder Superfamily
Class Class 4111

Cousin Family NamesSeedsMembers
Purine nucleoside phosphorylase inhibitor 2-amino-6-[(3-methyl... 3 1
Purine nucleoside phosphorylase inhibitor 2-amino-6-benzyl-1,7... 3 2


External ID

Functional Category

Molecule Name

CFAMM00374175 CHEMBL159271 Bioactive 2-amino-6-(thiophen-3-ylmethyl)-1,7-dihydropyrrolo[3,2-d]pyrimidin-4-one
CFAMM00374174 CHEMBL349855 Bioactive 2-amino-6-(thiophen-2-ylmethyl)-1,7-dihydropyrrolo[3,2-d]pyrimidin-4-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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