CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6694
Family Name Carbonic anhydrase 12 and Carbonic anhydrase 2 inhibitor (E)-2-cyano-3-(3,4-dimethoxyphenyl)-N-(4-sulfamoylphenyl)prop-2-enamide family
No. of Seeds 5 No. of Other Members 6
Family Centroid CFAMM00374399 Functional Category Bioactive
Superfamily Carbonic anhydrase 12 and Beta-lactamase Binder Superfamily
Class Class 3032

Cousin Family NamesSeedsMembers
Stromelysin-1 Inhibitor PG-530742 Family 4 23
D(4) dopamine receptor Ligand PD-165167 Family 2 96
D(2) dopamine receptor Ligand Rotigotine Patch Family 1 2
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-(... 7 18
Macrophage migration inhibitory factor Inhibitor 2-(4-hydroxys... 8 19
Amine oxidase [flavin-containing] B Inhibitor N-methyl-n-pheny... 6 25
Matrix metalloproteinase-9 and Collagenase 3 inhibitor 2-[benz... 9 9
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 5 3
Survival motor neuron protein and Retinal dehydrogenase 1 inhi... 1 2
Prelamin-A/C and Cellular tumor antigen p53 inhibitor CHEMBL15... 1 2
Carbonic anhydrase 9 and Carbonic anhydrase 14 inhibitor N-[2-... 6 10
Neprilysin inhibitor AGN-PC-047EOU family 1 0
Bone morphogenetic protein 1 inhibitor 3-[[4-(benzylcarbamoyla... 1 9
Carbonic anhydrase 12 and Carbonic anhydrase 9 inhibitor (E)-2... 3 2
Carbonic anhydrase 9 and Carbonic anhydrase 12 inhibitor (E)-2... 2 1
Carbonic anhydrase 9 and Carbonic anhydrase 12 inhibitor 2-(4-... 3 2
Carbonic anhydrase 2 and Carbonic anhydrase 9 inhibitor zinc;4... 2 5
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-benzo... 6 7
Histone deacetylase 3 and Histone deacetylase 9 inhibitor (2E,... 4 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00374399 CHEMBL2337528 Bioactive (E)-2-cyano-3-(3,4-dimethoxyphenyl)-N-(4-sulfamoylphenyl)prop-2-enamide
CFAMM00374389 CHEMBL2337535 Bioactive (E)-3-(1,3-benzodioxol-5-yl)-2-cyano-N-(4-sulfamoylphenyl)prop-2-enamide
CFAMM00374397 CHEMBL1594453 Bioactive (E)-2-cyano-3-(2-methoxyphenyl)-N-(4-sulfamoylphenyl)prop-2-enamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27511 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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