CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6708
Family Name Pol polyprotein inhibitor AC1NQUJL family
No. of Seeds 10 No. of Other Members 11
Family Centroid CFAMM00374456 Functional Category Bioactive
Superfamily Pol polyprotein Binder Superfamily 25
Class Class 3387

Cousin Family NamesSeedsMembers
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Plasmepsin-1 and Plasmepsin-2 Inhibitor PS-777621 Family 11 13
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 13
Disintegrin and metalloproteinase domain-containing protein 17... 10 39
Cathepsin K inhibitor SureCN6578603 family 1 3
Pol polyprotein inhibitor morpholinone scaffold 1 family 5 29
Pol polyprotein inhibitor benzyl (2S)-2-[[[(2S)-3-[cyclopentyl... 2 6
Matrix metalloproteinase-9 and Collagenase 3 inhibitor AGN-PC-... 7 12
Calpain-1 catalytic subunit and Cathepsin B inhibitor AGN-PC-0... 6 1
Calpain-2 catalytic subunit and Calpain-1 catalytic subunit in... 6 1
Pol polyprotein inhibitor AC1LA9K7 family 7 23
Pol polyprotein inhibitor AC1LA6RA family 4 12
72 kDa type IV collagenase and Collagenase 3 inhibitor (2R,4S)... 3 0
Carbonic anhydrase 9 and Carbonic anhydrase 14 inhibitor N-[2-... 6 10
Pol polyprotein inhibitor arylsulfonamide 10c family 17 2
C-C chemokine receptor type 5 ligand benzyl N-[1-[(3S)-4-[benz... 13 3
Pol polyprotein inhibitor AC1O41ZS family 2 0
Pol polyprotein inhibitor AGN-PC-075V7I family 7 1
Kappa-type opioid receptor and Cytochrome P450 2D6 ligand N-[(... 1 0
Beta-secretase 1 and Cathepsin B inhibitor N-[(2S)-1-[[(2S,3R)... 2 1
Matrix metalloproteinase-9 and Neutrophil collagenase inhibito... 3 0
Pol polyprotein inhibitor N-[2-Hydroxy-2-(8-Isopropyl-6,9-Diox... 7 6
72 kDa type IV collagenase and Collagenase 3 inhibitor SureCN7... 5 2
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 10 2
C-C chemokine receptor type 5 ligand phenyl N-[1-[(3S)-4-[benz... 2 5
Pol polyprotein inhibitor AC1LA9KP family 1 0
Pol polyprotein inhibitor [(3aR,6aS)-1,2,3,3a,4,5,6,6a-octahyd... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00374453 CHEMBL372059 Bioactive AC1NQUJR
CFAMM00374466 CHEMBL162086 Bioactive AC1LAPOC
CFAMM00374472 CHEMBL159580 Bioactive 4-methoxy-amprenavir
CFAMM00374464 CHEMBL365573 Bioactive AC1NQUJI
CFAMM00374470 CHEMBL336684 Bioactive AC1LA9K2
CFAMM00374456 CHEMBL190779 Bioactive AC1NQUJL
CFAMM00374469 CHEMBL161005 Bioactive AC1LAPO9
CFAMM00374468 CHEMBL371589 Bioactive oxolan-3-yl N-[(2S,3R)-4-[cyclopentyloxy-(4-methoxyphenyl)sulfonylamino]-3-hydroxy-1-phenylbutan-2-yl]carbamate
CFAMM00374461 CHEMBL187387 Bioactive AC1NQUJO
CFAMM00374467 CHEMBL161644 Bioactive AC1LAPO6

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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