CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Corticotropin-releasing factor receptor 1 ligand 5-chloro-1-[(1R)-1-cyclopropylethyl]-3-[(2,5-dimethyl-6-pyrrolidin-1-ylpyridin-3-yl)amino]pyrazin-2-one family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00314184 Functional Category Bioactive
Superfamily Flupirtine Superfamily
Class Class 1189

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
Prothrombin inhibitor SureCN7371121 family 13 3
Prothrombin and Trypsin-1 inhibitor SureCN12636557 family 9 1
Prothrombin inhibitor AGN-PC-073GVF family 12 1
Prothrombin and Trypsin-1 inhibitor AGN-PC-073JJH family 5 7
Prothrombin and Trypsin-1 inhibitor N-[(6-amino-2-methylpyridi... 3 0


External ID

Functional Category

Molecule Name

CFAMM00314184 CHEMBL1085930 Bioactive 5-chloro-1-[(1R)-1-cyclopropylethyl]-3-[(2,5-dimethyl-6-pyrrolidin-1-ylpyridin-3-yl)amino]pyrazin-2-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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