CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6738
Family Name Thromboxane-A synthase and Prostacyclin synthase inhibitor (Z)-6-[2-[1-(2-cyano-4-fluorophenyl)-2-methylpropan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acid family
No. of Seeds 1 No. of Other Members 18
Family Centroid CFAMM00374619 Functional Category Bioactive
Superfamily Thromboxane-A synthase and Prostacyclin synthase inhibitor (Z)-6-[2-[1-(2-cyano-4-fluorophenyl)-2-methylpropan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acid Superfamily
Class Class 4465

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Bepotastine Family 2 2
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase inhibit... 2 24
Thromboxane A2 receptor and Thromboxane-A synthase ligand Ici ... 3 17
Endothelin-1 receptor ligand SureCN8118632 family 4 5
Thromboxane-A synthase inhibitor (E)-7-[4-[5-[(2S,4S,5R)-5-[(Z... 3 9
Thromboxane-A synthase and Thromboxane A2 receptor ligand (Z)-... 2 10
Thromboxane-A synthase inhibitor (Z)-6-[2-[2-(benzenesulfonyl)... 2 0
Thromboxane-A synthase and Prostacyclin synthase inhibitor (Z)... 4 0
Thromboxane-A synthase and Prostacyclin synthase inhibitor (Z)... 2 2


External ID

Functional Category

Molecule Name

CFAMM00374619 CHEMBL159851 Bioactive (Z)-6-[2-[1-(2-cyano-4-fluorophenyl)-2-methylpropan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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