CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6808
Family Name Cannabinoid receptor 2 ligand 4-methyl-3-piperidin-1-ylsulfonyl-N-[2-(trifluoromethyl)phenyl]benzamide family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00375048 Functional Category Bioactive
Superfamily Carbonic anhydrase 2 and Carbonic anhydrase 7 Binder Superfamily
Class Class 3739

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A and Sigma non-opioid intracell... 7 28
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Caspase-3 Inhibitor 5-(pyrrolidin-1-ylsulfonyl)indoline-2,3-di... 5 35
72 kDa type IV collagenase Inhibitor SC-74020 Family 1 21
Carbonic anhydrase 2 Inhibitor N-benzyl-4-sulfamoyl-benzamide ... 12 44
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor N-(4-s... 12 92
Potassium voltage-gated channel subfamily A member 5 Ligand N-... 8 32
Integrin beta-3 Inhibitor L-750034 Family 7 38
C-C chemokine receptor type 8 Ligand N-(4-phenylsulfamoyl-naph... 4 62
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-p... 6 19
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-p... 5 10
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-p... 7 2
72 kDa type IV collagenase and Collagenase 3 inhibitor SureCN7... 1 8
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-04TGG7 family 2 3
Neutrophil elastase inhibitor SureCN7448165 family 2 4
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor 2,2,3,... 2 1
Apolipoprotein B-100 and Microsomal triglyceride transfer prot... 3 0
Apolipoprotein B-100 and Microsomal triglyceride transfer prot... 6 5
Cellular tumor antigen p53 inhibitor CHEMBL1554992 family 1 0
D(2) dopamine receptor and D(3) dopamine receptor ligand 1,1-d... 2 7
Coagulation factor X and Trypsin-1 inhibitor SureCN6161266 family 2 28
B1 bradykinin receptor ligand SureCN1712821 family 5 3
Transient receptor potential cation channel subfamily V member... 9 38
Inosine-5'-monophosphate dehydrogenase 2 inhibitor SureCN32339... 2 2
Bifunctional epoxide hydrolase 2 inhibitor 1-(2,4-dimethylphen... 4 8
Bifunctional epoxide hydrolase 2 inhibitor N-(2-chlorophenyl)-... 2 1
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltra... 5 10
Cannabinoid receptor 2 ligand AGN-PC-04VLWN family 9 4
Cannabinoid receptor 2 ligand N-cyclohexyl-4-propan-2-yl-3-pyr... 2 2
Coagulation factor X and Trypsin-1 inhibitor SureCN7690621 family 12 20
Carbonic anhydrase 2 inhibitor N-[(4-nitrophenyl)methyl]-4-sul... 1 2
Prostaglandin E2 receptor EP1 subtype and Prostaglandin D2 rec... 1 4
C-C chemokine receptor type 8 ligand 3-pyrrolidin-1-ylpropyl 4... 2 0
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibi... 1 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor KB-74... 2 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 0
Protein-glutamine gamma-glutamyltransferase 2 and Coagulation ... 3 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00375048 CHEMBL253260 Bioactive 4-methyl-3-piperidin-1-ylsulfonyl-N-[2-(trifluoromethyl)phenyl]benzamide
CFAMM00375046 CHEMBL253463 Bioactive 4-methyl-N-(2-methylsulfonylphenyl)-3-piperidin-1-ylsulfonylbenzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27433 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543