CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6826
Family Name Cell division cycle 7-related protein kinase inhibitor AGN-PC-04XLFJ family
No. of Seeds 6 No. of Other Members 6
Family Centroid CFAMM00375174 Functional Category Bioactive
Superfamily Inhibitor of nuclear factor kappa-B kinase subunit beta Inhibitor 6-phenyl-thieno[3,2-d]pyrimidin-4-ylamine Superfamily
Class Class 1151

Cousin Family NamesSeedsMembers
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 9 11
TGF-beta receptor type-1 Ligand 4-pyridin-2-yl-5-quinolin-4-yl... 4 23
Inhibitor of nuclear factor kappa-B kinase subunit beta Inhibi... 6 64
Cyclin-dependent kinase 5 Inhibitor 1-phenyl-3-(2-(pyridin-4-y... 3 53
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-chlo... 11 20
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 4 22
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 55
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 8 6
5-hydroxytryptamine receptor 6 ligand AGN-PC-03P3TZ family 6 88
Vascular endothelial growth factor receptor 2 and Mast/stem ce... 10 27
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-speci... 6 11
DNA-(apurinic or apyrimidinic site) lyase and Neuropeptide S r... 1 4
Adenosine kinase inhibitor SureCN8183719 family 2 3
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 5 27
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 7 21
TGF-beta receptor type-1 ligand 6-[(5E)-5-(4-methyl-3H-1,3-thi... 22 9
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor 2-[3-(1,4-di... 3 3
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 2 7
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 2 7
Prostaglandin G/H synthase 2 inhibitor 2-(4-methylsulfonylphen... 1 0
Adenosine receptor A2a and Adenosine receptor A2b ligand SureC... 4 5
Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70... 4 1
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 2 4
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 1 10
Aurora kinase A and Vascular endothelial growth factor recepto... 1 1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 5 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00375174 CHEMBL444981 Bioactive AGN-PC-04XLFJ
CFAMM00375173 CHEMBL463118 Bioactive AGN-PC-04XLFK
CFAMM00375178 CHEMBL505372 Bioactive AGN-PC-00M3DL
CFAMM00375177 CHEMBL463117 Bioactive AGN-PC-04XLFM
CFAMM00375183 CHEMBL510238 Bioactive AGN-PC-04XLFL
CFAMM00375175 CHEMBL449600 Bioactive ZINC00084214

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27260 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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