CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6852
Family Name 5-hydroxytryptamine receptor 1A ligand SureCN7763400 family
No. of Seeds 4 No. of Other Members 9
Family Centroid CFAMM00375373 Functional Category Bioactive with Natural Product
Superfamily 5-hydroxytryptamine receptor 1A ligand SureCN7763400 Superfamily
Class Class 296

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Hexylcaine ... 4 94
Dopamine reuptake and Noradrenergic re-uptake Inhibitor Cocain... 13 136
Cholinesterase Inhibitor 4-[4-(benzyloxy)piperidino]butyl-3-fl... 5 18
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 18 13
3-oxo-5-alpha-steroid 4-dehydrogenase 2 and 3-oxo-5-alpha-ster... 2 7
Sodium-dependent serotonin transporter and Transporter inhibit... 2 4
ATP-sensitive inward rectifier potassium channel 1 and Potassi... 3 3
Urotensin-2 inhibitor 3-(4-bromophenyl)-3-[2-(dimethylamino)et... 2 0


External ID

Functional Category

Molecule Name

CFAMM00375378 CHEMBL86648 Bioactive methyl (7R)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalene-1-carboxylate
CFAMM00375377 CHEMBL160924 Bioactive SureCN12531535
CFAMM00375370 CHEMBL316050 Bioactive methyl (7S)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalene-1-carboxylate
CFAMM00375373 CHEMBL26835 Bioactive SureCN7763400

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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