CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6865
Family Name 5-hydroxytryptamine receptor 2A and Alpha-1B adrenergic receptor ligand [(6aR,9R,10aR)-7-methyl-4-propan-2-yl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-9-yl]methyl cyclopropanecarboxylate;(Z)-but-2-enedioic acid family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00375421 Functional Category Bioactive
Superfamily Alpha-1B adrenergic receptor and 5-hydroxytryptamine receptor 2A Binder Superfamily
Class Class 1218

Cousin Family NamesSeedsMembers
D(2) dopamine receptor and D(1A) dopamine receptor ligand ergo... 12 720
D(1A) dopamine receptor ligand ergot alkaloid Methylergonovine... 22 170
D(2) dopamine receptor ligand ergot alkaloid Cabergoline Family 5 74
Muscarinic acetylcholine receptor M4 Ligand Tropicamide Family 3 73
Proteinase-activated receptor 1 Ligand SCH-530348 Family 20 215
Toll-like receptor 9 Ligand TLR9 Agonist Family 8 8
D(1B) dopamine receptor Ligand LE-300 Family 65 452
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1 4
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 5 23
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 6 24
Sodium-dependent serotonin transporter Inhibitor 3-(3-aminocyc... 94 23
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 6 10
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand (6-ben... 2 5
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 4 12
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 3 18
Sodium-dependent serotonin transporter and Sodium-dependent do... 6 4
5-hydroxytryptamine receptor 2A and Alpha-1B adrenergic recept... 10 9
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 2 1
Glucocorticoid receptor ligand SureCN5650626 family 17 25
Sodium-dependent serotonin transporter and Sodium-dependent do... 1 0
CGMP-dependent protein kinase inhibitor AGN-PC-075XII family 25 7
CGMP-dependent protein kinase inhibitor AGN-PC-075XJ0 family 9 1
5-hydroxytryptamine receptor 2A ligand (3R,4R)-3-(2-phenyl-1H-... 1 18
5-hydroxytryptamine receptor 1D ligand AGN-PC-01NTBS family 1 1
5-hydroxytryptamine receptor 2A and Alpha-1B adrenergic recept... 1 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 5 7


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00375424 CHEMBL2323581 Bioactive (6aR,9R,10aR)-9-(dimethoxymethyl)-4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline
CFAMM00375423 CHEMBL345374 Bioactive [(6aR,9R,10aR)-7-methyl-4-propan-2-yl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-9-yl]methyl cyclobutanecarboxylate;(Z)-but-2-enedioic acid
CFAMM00375421 CHEMBL347660 Bioactive [(6aR,9R,10aR)-7-methyl-4-propan-2-yl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-9-yl]methyl cyclopropanecarboxylate;(Z)-but-2-enedioic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48705 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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