CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6874
Family Name cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor 4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic Acid family
No. of Seeds 4 No. of Other Members 4
Family Centroid CFAMM00375449 Functional Category Bioactive with Natural Product
Superfamily Muscleblind-like protein 1 and Mitogen-activated protein kinase 14 Binder Superfamily
Class Class 3266

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Dolasetron Family 12 171
Histamine H1 receptor Ligand (s)-(+)-dimethindene Maleate Family 6 12
Dihydroorotate dehydrogenase Inhibitor Brequinar Family 9 122
Retinoic acid receptor alpha Ligand LG100268 Family 2 33
Dihydroorotate dehydrogenase Inhibitor Cinchoninic Acid Family 1 21
Lethal factor Inhibitor 3-(2,5-dimethyl-1h-pyrrol-1-yl)benzoic... 2 44
Egl nine homolog 2 Inhibitor Pyridine-2,4-dicarboxylic Acid Fa... 2 21
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 24 64
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand Isoqui... 1 6
Prostaglandin E2 receptor EP4 subtype and Prostaglandin D2 rec... 8 17
NS5B protein inhibitor AC1NQMYG family 6 12
Retinoic acid receptor alpha and Retinoic acid receptor beta l... 1 2
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand [(4S,... 5 2
NS5B protein inhibitor AC1NQMYP family 5 0
Egl nine homolog 1 inhibitor 2-[5-methyl-6-[[1-oxo-2-(4-phenyl... 4 3
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 1 2
Beta-3 adrenergic receptor ligand SureCN5704018 family 4 1
Serine/threonine-protein kinase Sgk1 inhibitor SureCN3774571 f... 2 18
Methionine aminopeptidase 1 inhibitor ethyl 4-[4-(2-pyridin-2-... 2 3
Transmembrane prolyl 4-hydroxylase inhibitor 2,2'-Bipyridine-5... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00375445 CHEMBL161115 Bioactive 4-[8-(3-chlorophenyl)-1,7-naphthyridin-6-yl]benzoic acid
CFAMM00375450 CHEMBL161740 Bioactive SureCN7018568
CFAMM00375449 CHEMBL74078 Bioactive 4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic Acid
CFAMM00375448 CHEMBL77826 Bioactive SureCN4962680

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26400 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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