CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6914
Family Name Bile acid receptor ligand 4-[[(2S)-2-[2-(4-chlorophenyl)-5,6-difluorobenzimidazol-1-yl]-2-cyclohexylacetyl]amino]-3-(trifluoromethyl)benzoic acid family
No. of Seeds 4 No. of Other Members 12
Family Centroid CFAMM00375688 Functional Category Bioactive
Superfamily NS5B protein and Bile acid receptor Binder Superfamily
Class Class 1253

Cousin Family NamesSeedsMembers
Type-1 angiotensin II receptor Ligand Telmisartan Family 4 181
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 2 9
Bile acid receptor and Potassium voltage-gated channel subfami... 2 1
Dipeptidyl peptidase 4 inhibitor 2-[(3R)-3-aminopiperidin-1-yl... 7 15
Melanocortin receptor 4 ligand AGN-PC-076AMT family 2 9
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 5
Glucokinase inhibitor 6-[[(2S)-3-cyclopentyl-2-[4-(trifluorome... 1 1
Tyrosine-protein kinase Lck inhibitor AGN-PC-074LPB family 2 0
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00375686 CHEMBL1668259 Bioactive 4-[[(2S)-2-[2-(4-chlorophenyl)benzimidazol-1-yl]-2-cyclohexylacetyl]amino]-3-(trifluoromethyl)benzoic acid
CFAMM00375699 CHEMBL1615154 Bioactive 4-[[(2S)-2-[2-(4-chlorophenyl)-5,6-difluorobenzimidazol-1-yl]-2-cyclohexylacetyl]amino]-3,5-difluorobenzoic acid
CFAMM00375695 CHEMBL1668243 Bioactive 3-chloro-4-[[(2S)-2-[2-(4-chlorophenyl)-5,6-difluorobenzimidazol-1-yl]-2-cyclohexylacetyl]amino]benzoic acid
CFAMM00375688 CHEMBL1668244 Bioactive 4-[[(2S)-2-[2-(4-chlorophenyl)-5,6-difluorobenzimidazol-1-yl]-2-cyclohexylacetyl]amino]-3-(trifluoromethyl)benzoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27257 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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