CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6918
Family Name Serine/threonine-protein kinase mTOR and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform inhibitor AGN-PC-079OJR family
No. of Seeds 13 No. of Other Members 2
Family Centroid CFAMM00375735 Functional Category Bioactive
Superfamily DNA primase Inhibitor Bay 57-1293 Superfamily
Class Class 1446

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase C Inhibitor SNS-314 Family 2 75
Serine/threonine-protein kinase B-raf Inhibitor GSK2118436 Family 5 19
Metabotropic glutamate receptor 5 Ligand N-[4-(3-pyridylethyny... 2 10
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor 2-[3-(4-acet... 4 12
Mitogen-activated protein kinase 14 inhibitor AGN-PC-07ZXHN fa... 2 4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 8
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 0
Mitogen-activated protein kinase 14 inhibitor N-[4-[2-ETHYL-4-... 4 5
Vascular endothelial growth factor receptor 2 ligand N-(1,3-Th... 4 4
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor 2-[3-(1,4-di... 3 3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00375730 CHEMBL1773730 Bioactive AGN-PC-093OHJ
CFAMM00375735 CHEMBL1773605 Bioactive AGN-PC-079OJR
CFAMM00375727 CHEMBL1822052 Bioactive N-[5-(2-amino-1,3-benzothiazol-6-yl)-2-chloropyridin-3-yl]-4-fluorobenzenesulfonamide
CFAMM00375725 CHEMBL1773732 Bioactive AGN-PC-093OHL
CFAMM00375733 CHEMBL1773606 Bioactive AGN-PC-093OHG
CFAMM00375732 CHEMBL1773735 Bioactive AGN-PC-093OOT
CFAMM00375731 CHEMBL1773734 Bioactive AGN-PC-093OOS

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27759 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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