CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM693
Family Name Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform inhibitor AGN-PC-00IVC7 family
No. of Seeds 23 No. of Other Members 48
Family Centroid CFAMM00314357 Functional Category Bioactive
Superfamily DNA-dependent protein kinase catalytic subunit and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Binder Superfamily
Class Class 1558

Cousin Family NamesSeedsMembers
DNA-dependent protein kinase catalytic subunit and Phosphatidy... 1 6
DNA-dependent protein kinase catalytic subunit inhibitor 2-[4-... 2 4
DNA-dependent protein kinase catalytic subunit inhibitor 2-[et... 3 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00314335 CHEMBL2420446 Bioactive 2-[4-[2-(2-hydroxyethoxy)ethyl]piperazin-1-yl]-N-[4-(2-morpholin-4-yl-4-oxochromen-8-yl)dibenzothiophen-1-yl]acetamide
CFAMM00314374 CHEMBL2420315 Bioactive N-[4-(2-morpholin-4-yl-4-oxochromen-8-yl)dibenzothiophen-1-yl]-2-(4-propan-2-ylpiperazin-1-yl)acetamide
CFAMM00314387 CHEMBL2420439 Bioactive 2-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-N-[4-(2-morpholin-4-yl-4-oxochromen-8-yl)dibenzothiophen-1-yl]acetamide
CFAMM00314341 CHEMBL2420428 Bioactive 2-(2-hydroxyethylamino)-N-[4-(2-morpholin-4-yl-4-oxochromen-8-yl)dibenzothiophen-1-yl]acetamide
CFAMM00314354 CHEMBL2420292 Bioactive 3-[(4-methoxyphenyl)methylamino]-N-[4-(2-morpholin-4-yl-4-oxochromen-8-yl)dibenzothiophen-1-yl]propanamide
CFAMM00314334 CHEMBL2420441 Bioactive N-[4-(2-morpholin-4-yl-4-oxochromen-8-yl)dibenzothiophen-1-yl]-2-[2-(2-oxoimidazolidin-1-yl)ethylamino]acetamide
CFAMM00314360 CHEMBL2420299 Bioactive 3-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-N-[4-(2-morpholin-4-yl-4-oxochromen-8-yl)dibenzothiophen-1-yl]propanamide
CFAMM00314373 CHEMBL2420444 Bioactive 2-(4-acetylpiperazin-1-yl)-N-[4-(2-morpholin-4-yl-4-oxochromen-8-yl)dibenzothiophen-1-yl]acetamide
CFAMM00314340 CHEMBL2420308 Bioactive 2-[4-[2-(dimethylamino)ethyl]piperazin-1-yl]-N-[4-(2-morpholin-4-yl-4-oxochromen-8-yl)dibenzothiophen-1-yl]acetamide
CFAMM00314333 CHEMBL2420303 Bioactive 3-(2-methoxyethylamino)-N-[4-(2-morpholin-4-yl-4-oxochromen-8-yl)dibenzothiophen-1-yl]propanamide
CFAMM00314359 CHEMBL2420426 Bioactive 2-[bis(2-hydroxyethyl)amino]-N-[4-(2-morpholin-4-yl-4-oxochromen-8-yl)dibenzothiophen-1-yl]acetamide
CFAMM00314352 CHEMBL2420294 Bioactive 3-amino-N-[4-(2-morpholin-4-yl-4-oxochromen-8-yl)dibenzothiophen-1-yl]propanamide
CFAMM00314378 CHEMBL2420276 Bioactive N-[4-(2-morpholin-4-yl-4-oxochromen-8-yl)dibenzothiophen-1-yl]-3-(3-morpholin-4-ylpropylamino)propanamide
CFAMM00314332 CHEMBL2420443 Bioactive 2-(2-methoxyethylamino)-N-[4-(2-morpholin-4-yl-4-oxochromen-8-yl)dibenzothiophen-1-yl]acetamide
CFAMM00314351 CHEMBL2420295 Bioactive 3-(2-morpholin-4-ylethylamino)-N-[4-(2-morpholin-4-yl-4-oxochromen-8-yl)dibenzothiophen-1-yl]propanamide
CFAMM00314338 CHEMBL2420445 Bioactive 2-[4-(2-methoxyethyl)piperazin-1-yl]-N-[4-(2-morpholin-4-yl-4-oxochromen-8-yl)dibenzothiophen-1-yl]acetamide
CFAMM00314331 CHEMBL2420301 Bioactive N-[4-(2-morpholin-4-yl-4-oxochromen-8-yl)dibenzothiophen-1-yl]-3-[2-(2-oxoimidazolidin-1-yl)ethylamino]propanamide
CFAMM00314357 CHEMBL1086377 Bioactive AGN-PC-00IVC7
CFAMM00314370 CHEMBL2420310 Bioactive 2-[4-(2-hydroxyethyl)piperazin-1-yl]-N-[4-(2-morpholin-4-yl-4-oxochromen-8-yl)dibenzothiophen-1-yl]acetamide
CFAMM00314337 CHEMBL2420307 Bioactive N-[4-(2-morpholin-4-yl-4-oxochromen-8-yl)dibenzothiophen-1-yl]-2-[4-[2-oxo-3-(propan-2-ylamino)propyl]piperazin-1-yl]acetamide
CFAMM00314350 CHEMBL2420296 Bioactive N-[4-(2-morpholin-4-yl-4-oxochromen-8-yl)dibenzothiophen-1-yl]-3-(oxolan-2-ylmethylamino)propanamide
CFAMM00314382 CHEMBL2420272 Bioactive 3-[4-[2-(dimethylamino)ethyl]piperazin-1-yl]-N-[4-(2-morpholin-4-yl-4-oxochromen-8-yl)dibenzothiophen-1-yl]propanamide
CFAMM00314329 CHEMBL2420321 Bioactive 3-(2-hydroxyethylamino)-N-[4-(2-morpholin-4-yl-4-oxochromen-8-yl)dibenzothiophen-1-yl]propanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27619 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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