CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6933
Family Name Bifunctional dihydrofolate reductase-thymidylate synthase inhibitor 3-(2,6-diamino-5-phenylpyrimidin-4-yl)propyl benzoate family
No. of Seeds 2 No. of Other Members 12
Family Centroid CFAMM00375876 Functional Category Bioactive with Natural Product
Superfamily Cholinesterase and Beta-lactamase Binder Superfamily
Class Class 3698

Cousin Family NamesSeedsMembers
Arachidonate 5-lipoxygenase Inhibitor Methyl 2-(benzylamino)-1... 3 10
Survival motor neuron protein inhibitor CHEMBL1581561 family 1 3
Dipeptidyl peptidase 4 inhibitor 3-[6-[(3R,4S)-3-amino-4-(2,4,... 3 7
Scavenger receptor class B member 1 ligand methyl 9-[3-(4,6-di... 2 10
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 9 6
Growth hormone secretagogue receptor type 1 ligand SureCN62436... 8 6
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 1 14
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 2 0
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00375865 CHEMBL346932 Bioactive AGN-PC-009M2L
CFAMM00375876 CHEMBL162126 Bioactive 3-(2,6-diamino-5-phenylpyrimidin-4-yl)propyl benzoate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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