CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6938
Family Name Carbonic anhydrase 2 inhibitor (2-sulfamoyl-1-benzofuran-5-yl) acetate family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00375923 Functional Category Bioactive with Natural Product
Superfamily Carbonic anhydrase 2 Binder Superfamily 6
Class Class 628

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Fenoprofen Family 4 1077
Estrogen receptor beta Ligand 2-(4-hydroxy-phenyl)benzofuran-5... 5 82
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 2,5-... 2 96
Oestrogen receptor and Estrogen receptor beta Ligand 7-chloro-... 2 27
Platelet-derived growth factor receptor beta Ligand Bis(5-meth... 5 220
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 3-ben... 4 74
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Carbonic anhydrase 2 inhibitor (2-sulfamoyl-1-benzofuran-6-yl)... 2 8
ELAV-like protein 1 and Myosin light chain kinase, smooth musc... 1 32
Arachidonate 5-lipoxygenase inhibitor 7-[[3-fluoro-5-(3-hydrox... 2 10
Sodium-dependent serotonin transporter and Sodium-dependent do... 3 78


External ID

Functional Category

Molecule Name

CFAMM00375926 CHEMBL352281 Bioactive (2-sulfamoyl-1-benzofuran-5-yl) 2,2-dimethylpropanoate
CFAMM00375925 CHEMBL349815 Bioactive 5-hydroxy-1-benzofuran-2-sulfonamide
CFAMM00375923 CHEMBL165124 Bioactive (2-sulfamoyl-1-benzofuran-5-yl) acetate
CFAMM00375928 CHEMBL162280 Bioactive 5-methoxy-1-benzofuran-2-sulfonamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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