CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6939
Family Name Trypsin-1 and Trypsin-2 inhibitor 4-[3-[(3S)-3-(2,3-dihydro-1-benzofuran-5-ylsulfonylamino)-2-oxoazepan-1-yl]-2-oxopropyl]benzenecarboximidamide family
No. of Seeds 3 No. of Other Members 7
Family Centroid CFAMM00375929 Functional Category Bioactive
Superfamily Trypsin-1 and Prothrombin Binder Superfamily 6
Class Class 4485

Cousin Family NamesSeedsMembers
Trypsin-1 and Trypsin-2 inhibitor CHEMBL163312 family 1 1
Prothrombin and Trypsin-1 inhibitor 4-[3-[(3S)-3-[(2,5-dimetho... 2 1
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-2-... 2 0
Prothrombin inhibitor 4-[3-[(3S)-3-[(3,4-dimethoxyphenyl)sulfo... 1 2


External ID

Functional Category

Molecule Name

CFAMM00375936 CHEMBL162289 Bioactive 4-[3-[(3S)-3-(2,3-dihydro-1-benzofuran-5-ylsulfonylamino)-2-oxoazepan-1-yl]-2-oxopropyl]-3-fluorobenzenecarboximidamide
CFAMM00375929 CHEMBL354456 Bioactive 4-[3-[(3S)-3-(2,3-dihydro-1-benzofuran-5-ylsulfonylamino)-2-oxoazepan-1-yl]-2-oxopropyl]benzenecarboximidamide
CFAMM00375935 CHEMBL162452 Bioactive 5-[3-[(3S)-3-(2,3-dihydro-1-benzofuran-5-ylsulfonylamino)-2-oxoazepan-1-yl]-2-oxopropyl]thiophene-2-carboximidamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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