CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6951
Family Name Androgen receptor ligand (6R,7S)-6-ethyl-7-methyl-4-(trifluoromethyl)-6,7,8,9-tetrahydro-1H-pyrido[3,2-g]quinolin-2-one family
No. of Seeds 22 No. of Other Members 29
Family Centroid CFAMM00376072 Functional Category Bioactive
Superfamily Cholinesterase and Androgen receptor Binder Superfamily
Class Class 770

Cousin Family NamesSeedsMembers
Histamine N-methyltransferase inhibitor aminoquinoline Amodiaq... 8 23
DNA Binder Elliptinium Acetate Family 11 116
5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine recept... 11 41
Oestrogen receptor and Estrogen receptor beta Ligand 4-(3-phen... 5 14
E3 ubiquitin-protein ligase Mdm2 Inhibitor NSC-66811 Family 4 27
Acetylcholinesterase and Cholinesterase Inhibitor 6-hydroxy-1,... 4 2
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 38 35
Kinesin-like protein KIF11 inhibitor AGN-PC-080PZM family 1 11
Glucocorticoid receptor ligand 4-fluoro-2-[5,5,5-trifluoro-4-h... 3 9
Survival motor neuron protein and Ferritin light chain inhibit... 1 25
Methionine--tRNA ligase inhibitor SureCN7818124 family 1 9
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-09Q7W... 7 3
Alpha-2C adrenergic receptor and Alpha-2A adrenergic receptor ... 5 8
Acetylcholinesterase and Butyrylcholinesterase inhibitor (E)-3... 4 5
Androgen receptor ligand SureCN1771931 family 5 3
Transient receptor potential cation channel subfamily V member... 1 5
Acetylcholinesterase inhibitor CHEMBL79874 family 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00376071 CHEMBL7177 Bioactive (8R)-8-ethyl-4-(trifluoromethyl)-6,7,8,9-tetrahydro-1H-pyrido[3,2-g]quinolin-2-one
CFAMM00376064 CHEMBL283449 Bioactive 6-methyl-4-(trifluoromethyl)-6,7,8,9-tetrahydro-1H-pyrido[3,2-g]quinolin-2-one
CFAMM00376044 CHEMBL27812 Bioactive CHEMBL27812
CFAMM00376050 CHEMBL6959 Bioactive (7S,8R)-7,8-diethyl-4-(trifluoromethyl)-6,7,8,9-tetrahydro-1H-pyrido[3,2-g]quinolin-2-one
CFAMM00376077 CHEMBL431493 Bioactive (4aR,12bS)-11-(trifluoromethyl)-2,3,4,4a,5,6,8,12b-octahydro-1H-pyrido[3,2-b]phenanthridin-9-one
CFAMM00376035 CHEMBL282204 Bioactive (7S)-6,7-dimethyl-4-(trifluoromethyl)-6,7,8,9-tetrahydro-1H-pyrido[3,2-g]quinolin-2-one
CFAMM00376076 CHEMBL27276 Bioactive 6-propan-2-yl-4-(trifluoromethyl)-6,7,8,9-tetrahydro-1H-pyrido[3,2-g]quinolin-2-one
CFAMM00376062 CHEMBL418198 Bioactive (7R)-6-ethyl-7-methyl-4-(trifluoromethyl)-6,7,8,9-tetrahydro-1H-pyrido[3,2-g]quinolin-2-one
CFAMM00376041 CHEMBL7383 Bioactive (6S,8R)-6,8-diethyl-4-(trifluoromethyl)-6,7,8,9-tetrahydro-1H-pyrido[3,2-g]quinolin-2-one
CFAMM00376068 CHEMBL266269 Bioactive (7R,8R)-7-ethyl-8-methyl-4-(trifluoromethyl)-6,7,8,9-tetrahydro-1H-pyrido[3,2-g]quinolin-2-one
CFAMM00376034 CHEMBL267141 Bioactive (8R)-8-methyl-4-(trifluoromethyl)-6,7,8,9-tetrahydro-1H-pyrido[3,2-g]quinolin-2-one
CFAMM00376054 CHEMBL351022 Bioactive 3,3-dimethyl-5-(trifluoromethyl)-2,8-dihydro-1H-pyrrolo[3,2-g]quinolin-7-one
CFAMM00376067 CHEMBL281945 Bioactive (7R)-7-methyl-4-(trifluoromethyl)-6-(3,3,3-trifluoropropyl)-6,7,8,9-tetrahydro-1H-pyrido[3,2-g]quinolin-2-one
CFAMM00376033 CHEMBL162569 Bioactive (2R,3R)-2,3-dimethyl-5-(trifluoromethyl)-1,2,3,8-tetrahydropyrrolo[3,2-g]quinolin-7-one
CFAMM00376066 CHEMBL351465 Bioactive (2R)-2-methyl-5-(trifluoromethyl)-1,2,3,8-tetrahydropyrrolo[3,2-g]quinolin-7-one
CFAMM00376032 CHEMBL345854 Bioactive 6-(trifluoromethyl)spiro[1,3,4,9-tetrahydropyrido[3,2-g]quinoline-2,1'-cyclohexane]-8-one
CFAMM00376059 CHEMBL7053 Bioactive (7S,8R)-7-ethyl-8-methyl-4-(trifluoromethyl)-6,7,8,9-tetrahydro-1H-pyrido[3,2-g]quinolin-2-one
CFAMM00376072 CHEMBL2113261 Bioactive (6R,7S)-6-ethyl-7-methyl-4-(trifluoromethyl)-6,7,8,9-tetrahydro-1H-pyrido[3,2-g]quinolin-2-one
CFAMM00376038 CHEMBL436344 Bioactive (7R)-6,7-dimethyl-4-(trifluoromethyl)-6,7,8,9-tetrahydro-1H-pyrido[3,2-g]quinolin-2-one
CFAMM00376052 CHEMBL25802 Bioactive (4aS,12bS)-11-(trifluoromethyl)-2,3,4,4a,5,6,8,12b-octahydro-1H-pyrido[3,2-b]phenanthridin-9-one
CFAMM00376065 CHEMBL268326 Bioactive (6S,8R)-6,8-dimethyl-4-(trifluoromethyl)-6,7,8,9-tetrahydro-1H-pyrido[3,2-g]quinolin-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27298 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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