CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6952
Family Name Serine/threonine-protein kinase D3 and Protein kinase C delta type inhibitor 3-[2-(1-benzothiophen-2-yl)-3-(4-cyano-2,5-dioxopyrrol-3-yl)indol-1-yl]propyl carbamimidothioate family
No. of Seeds 3 No. of Other Members 10
Family Centroid CFAMM00376090 Functional Category Bioactive
Superfamily Coagulation factor X and Coagulation factor IX Binder Superfamily 2
Class Class 1481

Cousin Family NamesSeedsMembers
Hepatocyte growth factor receptor Ligand Arq 197 Family 10 400
Glycogen synthase kinase-3 beta and Protein kinase C beta type... 5 53
Cyclin-dependent kinase 1 and G2/mitotic-specific cyclin-B1 In... 2 0
Dipeptidyl peptidase 1 inhibitor (2S)-2-amino-N-[(1S)-1-cyano-... 2 14
Neuropeptide S receptor and Prelamin-A/C ligand CHEMBL1367658 ... 1 7
Nuclear receptor ROR-gamma and Niemann-Pick C1 protein ligand ... 1 12
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor lig... 2 4
Serine/threonine-protein kinase D3 and Protein kinase C delta ... 3 0
Neuromedin-K receptor ligand 3-methylsulfinyl-N-[(1S)-1-phenyl... 3 5
Protein kinase C beta type and Protein kinase C delta type inh... 1 2
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-(1-... 2 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL3... 1 9


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00376090 CHEMBL162621 Bioactive 3-[2-(1-benzothiophen-2-yl)-3-(4-cyano-2,5-dioxopyrrol-3-yl)indol-1-yl]propyl carbamimidothioate
CFAMM00376095 CHEMBL162903 Bioactive SureCN9167725
CFAMM00376088 CHEMBL350335 Bioactive 3-[2-(1-benzothiophen-2-yl)-3-(2,5-dioxopyrrol-3-yl)indol-1-yl]propyl carbamimidothioate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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