CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6955
Family Name Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]-2-[(2-methylpyridine-3-carbonyl)amino]propanoic acid family
No. of Seeds 3 No. of Other Members 14
Family Centroid CFAMM00376115 Functional Category Bioactive
Superfamily Integrin beta-1 and Integrin alpha-4 Binder Superfamily 6
Class Class 2592

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 14 2769
HIV protease Inhibitor Saquinavir Family 64 428
Indoleamine 2,3-dioxygenase 1 Inhibitor L-tryptophan Family 8 328
Reverse transcriptase Inhibitor IDX899 Family 2 118
Integrin beta-3 Inhibitor Elarofiban Family 28 45
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
14-alpha sterol demethylase Inhibitor CP-320626 Family 13 76
Integrin beta-1 and Integrin alpha-4 Inhibitor MK-0668 Family 46 20
Endothelin B receptor Ligand IRL-2500 Family 34 87
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-[(3,5... 28 18
Cholecystokinin receptor type A ligand A-65186 family 2 6
Pol polyprotein inhibitor N-[(2S)-1-[[(2S,3R,4S,5S)-3,4-dihydr... 2 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(1-benz... 2 1
Integrin beta-1 and Integrin alpha-4 inhibitor (Z)-2-[[(4S)-3-... 2 1
Histone deacetylase 6 and Histone deacetylase 1 inhibitor 4-[(... 2 9
Integrin beta-1 and Integrin alpha-5 inhibitor (2S)-2-[(2,6-di... 6 5
C-C chemokine receptor type 5 ligand 4-[[[[1-[(2R)-4-[(6-chlor... 2 0
C-C chemokine receptor type 5 ligand 6-chloro-N-[(3R)-3-[4-[(5... 16 4
Integrin alpha-V and Integrin beta-6 inhibitor SureCN12259087 ... 3 4
Gastrin/cholecystokinin type B receptor ligand (2R)-2-[[5-(8-a... 2 3
Folylpolyglutamate synthase, mitochondrial and Dihydrofolate r... 3 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-[(3,5... 1 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(1-benz... 2 1
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN5367895 f... 3 0
Thymidylate synthase inhibitor (2S)-2-[[(4S)-4-carboxy-4-[[(4S... 1 7
Integrin beta-1 and Integrin alpha-5 inhibitor 2-[(2,6-dimethy... 9 1
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-[(2,6... 1 1
Glycogen phosphorylase, liver form inhibitor 2-[(1R,2R)-2-[(5-... 3 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00376115 CHEMBL311665 Bioactive (2S)-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]-2-[(2-methylpyridine-3-carbonyl)amino]propanoic acid
CFAMM00376110 CHEMBL313363 Bioactive (2S)-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]-2-[(2,4-dimethylpyridine-3-carbonyl)amino]propanoic acid
CFAMM00376116 CHEMBL162676 Bioactive (2S)-2-[(1-benzyl-5-oxopyrrolidine-2-carbonyl)amino]-3-[4-[(2-chloro-6-methylpyridine-3-carbonyl)amino]phenyl]propanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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