CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6979
Family Name Gastrin/cholecystokinin type B receptor ligand 1-[3-[[2-(3-methoxy-N-[2-(N-methylanilino)-2-oxoethyl]anilino)-2-oxoethyl]carbamoylamino]phenyl]ethanesulfonic acid family
No. of Seeds 2 No. of Other Members 12
Family Centroid CFAMM00376236 Functional Category Bioactive with Natural Product
Superfamily Collagenase 3 and Beta-lactamase Binder Superfamily
Class Class 3547

Cousin Family NamesSeedsMembers
Acetylcholinesterase Inhibitor Neostigmine Family 4 76
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Beta-3 adrenergic receptor Ligand Cgp 12177 Family 3 8
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Alpha-1 adrenergic receptor Ligand DC-015 Family 8 25
Glucose-6-phosphate 1-dehydrogenase Inhibitor Metazamide Family 9 69
Inosine-5'-monophosphate dehydrogenase Inhibitor VX-148 Family 2 3
Leukotriene A-4 hydrolase Inhibitor N5-[4-(phenylmethoxy)pheny... 7 49
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 11 20
Substance-K receptor Ligand MEN-14933 Family 13 154
Cannabinoid receptor 1 Ligand N-(4-methoxyphenyl)oleamide Family 4 23
Alpha-1A adrenergic receptor and D(2) dopamine receptor Ligand... 5 49
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Bifunctional epoxide hydrolase 2 Inhibitor 1-adamantan-1-yl-3-... 12 44
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Renin Inhibitor Ro-66-1168 Family 10 30
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
Leukotriene A-4 hydrolase Inhibitor 1-[4-(4-iodophenoxy)phenyl... 5 18
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Fatty-acid amide hydrolase 1 Inhibitor Phenmedipham Family 2 5
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 28
Tyrosinase Inhibitor 1-(4-(benzyloxy)phenyl)-3-hydroxyurea Family 9 23
Liver carboxylesterase 1 Inhibitor SCH-48375 Family 2 28
Integrin beta-1 and Integrin alpha-4 inhibitor (3S)-3-(3,4-dim... 5 61
Vasopressin V2 receptor and Vasopressin V1a receptor ligand AG... 1 7
Substance-P receptor ligand N-[1-[acetyl-[(2-methoxyphenyl)met... 3 9
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 10
Cathepsin K inhibitor N-[(2S)-1-(4-methoxyanilino)propan-2-yl]... 11 10
D(2) dopamine receptor ligand 7-[4-[4-(2-ethoxyphenyl)piperazi... 12 14
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 5 13
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-(3-... 4 6
C-C chemokine receptor type 3 ligand SureCN6705515 family 2 16
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 9 37
Transient receptor potential cation channel subfamily V member... 3 15
Survival motor neuron protein and DNA-(apurinic or apyrimidini... 1 5
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 3 1
Survival motor neuron protein and ATP-dependent DNA helicase Q... 1 4
Substance-P receptor ligand (2S,4S)-1-N-(3-chlorophenyl)-2-N-[... 5 2
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 2 4
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-088O2I family 3 3
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-088O2K family 2 0
Gonadotropin-releasing hormone receptor ligand SureCN5756131 f... 5 7
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 6 1
Renin and Cytochrome P450 3A4 inhibitor SureCN6719989 family 2 0
Cathepsin K and Cathepsin L1 inhibitor 4-ethyl-N-[(2S)-1-[2-(4... 7 10
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 4 19
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor [4-(2,... 2 11
Motilin receptor ligand SureCN14564469 family 1 6
Cathepsin K inhibitor (1R,2R)-N-(cyanomethyl)-2-[4-(3-methoxyp... 2 1
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 12 13
Translocator protein inhibitor CHEMBL2332259 family 2 0
C-X-C chemokine receptor type 3 ligand 1-[1-[(9-acetyl-9-azabi... 1 0
Neuropeptide Y receptor type 1 ligand SureCN8354018 family 2 2
Delta-type opioid receptor and Kappa-type opioid receptor liga... 5 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 4 7
Neuropeptide Y receptor type 5 ligand 1-[1-(4-fluorophenyl)pro... 2 8
Neuropeptide Y receptor type 5 ligand AGN-PC-01NRZ6 family 3 6
Substance-P receptor ligand CP 141938 family 1 0
Integrin beta-3 and Integrin alpha-V inhibitor SureCN7496449 f... 3 2
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 1 0
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-00RZQT family 3 4
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 2 0
Sterol O-acyltransferase 1 inhibitor SureCN6152927 family 7 3
Histamine H3 receptor ligand AGN-PC-07ZCFA family 1 0
Coagulation factor VII and Prothrombin inhibitor AGN-PC-0752KC... 3 3
C-C chemokine receptor type 3 ligand SureCN6700764 family 2 2
C-X-C chemokine receptor type 3 ligand 1-[1-[[(1S,5R)-6,6-dime... 2 3
Cholinesterase inhibitor (13-methyl-5,6,8,13a-tetrahydroisoqui... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00376236 CHEMBL1628621 Bioactive 1-[3-[[2-(3-methoxy-N-[2-(N-methylanilino)-2-oxoethyl]anilino)-2-oxoethyl]carbamoylamino]phenyl]ethanesulfonic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27255 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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