CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM6984
Family Name C5a anaphylatoxin chemotactic receptor 1 ligand N-[(4-dimethylaminophenyl)methyl]-7-methoxy-N-(4-propan-2-ylphenyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide family
No. of Seeds 1 No. of Other Members 4
Family Centroid CFAMM00376256 Functional Category Bioactive
Superfamily Liver carboxylesterase 1 and Voltage-dependent L-type calcium channel Binder Superfamily
Class Class 1560

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
Angiotensin-converting enzyme Inhibitor Moexipril Family 5 469
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
Voltage-dependent L-type calcium channel Ligand Sq32,910 Family 1 25
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 18 12
Oxytocin receptor and Vasopressin V1a receptor Ligand L-371257... 8 92
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 131
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Alpha-1A adrenergic receptor Ligand Naftopidil Family 15 119
Alpha-1A adrenergic receptor and D(2) dopamine receptor Ligand... 5 49
Histone deacetylase 2 Inhibitor N-(4-amino-3'-methoxybiphenyl-... 3 49
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Multidrug resistance protein 1 and Multidrug resistance-associ... 3 55
Urotensin-2 receptor Ligand JNJ-28318706 Family 4 227
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
Liver carboxylesterase 1 Inhibitor SCH-48375 Family 2 28
Integrin beta-1 and Integrin alpha-4 inhibitor (3S)-3-(3,4-dim... 5 61
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 2 6
Vasopressin V2 receptor and Vasopressin V1a receptor ligand AG... 1 7
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 14 12
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 49 8
D(2) dopamine receptor and 5-hydroxytryptamine receptor 2C lig... 2 2
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[3-... 4 2
Potassium voltage-gated channel subfamily H member 2 and Melan... 9 4
Prostaglandin D2 receptor 2 ligand SureCN136287 family 1 9
Cystic fibrosis transmembrane conductance regulator inhibitor ... 2 3
Histamine H3 receptor ligand 5-[4-[3-[(2R)-2-methylpyrrolidin-... 2 3
Cathepsin K and Cathepsin L1 inhibitor 4-ethyl-N-[(2S)-1-[2-(4... 7 10
Sphingosine 1-phosphate receptor 1 ligand 2-methoxy-N-[(4-phen... 2 23
Integrin beta-3 and Integrin alpha-2 inhibitor 3-(4-methoxyphe... 4 6
Somatostatin receptor type 1 and D(4) dopamine receptor ligand... 9 10
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 7 1
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 2 11
Delta-type opioid receptor and Kappa-type opioid receptor liga... 5 0
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 11 4
C-C chemokine receptor type 5 ligand dimethyl-[[4-[[7-(4-methy... 7 8
Capsid scaffolding protein inhibitor AC1MHP1L family 3 6
D(3) dopamine receptor ligand rac S 33138 family 1 0
Mitogen-activated protein kinase 14 inhibitor SureCN4822166 fa... 1 4
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 5 5
3-oxo-5-alpha-steroid 4-dehydrogenase 1 inhibitor AGN-PC-04F7M... 1 3
Aromatase inhibitor SureCN10351071 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00376256 CHEMBL1628668 Bioactive N-[(4-dimethylaminophenyl)methyl]-7-methoxy-N-(4-propan-2-ylphenyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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